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Erythema elevatum et diutinum as a systemic disease
Jeena K Sandhu1, Joerg Albrecht2, Gaurav Agnihotri3
1University of Missouri-Kansas City School of Medicine, Kansas City, Missouri, USA.
Clinics in Dermatology
|December 23, 2019
Summary
Erythema elevatum et diutinum (EED) is a rare skin condition potentially affecting multiple organs. Evaluating EED patients for systemic issues ensures comprehensive care and management of associated diseases.
Area of Science:
- Dermatology
- Immunology
- Rheumatology
Background:
- Erythema elevatum et diutinum (EED) is a rare, chronic skin disease.
- EED is frequently linked to various extracutaneous manifestations and systemic conditions.
Purpose of the Study:
- To highlight the systemic implications of EED.
- To emphasize the need for thorough evaluation of EED patients for extracutaneous involvement.
Main Methods:
- Literature review of EED cases with systemic associations.
- Analysis of reported extracutaneous findings in EED patients.
Main Results:
- EED is associated with arthralgias, scleritis, uveitis, keratitis, ulcers, and neuropathy.
- Systemic diseases linked to EED include HIV, IgA paraproteinemia, myelomas, neutrophilic dermatoses, and inflammatory bowel diseases.
Conclusions:
- EED may represent a multiorgan entity due to its widespread manifestations.
- Systemic evaluation is crucial for EED patients to guide targeted treatment and management.
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