Related Experiment Video

Updated: Jan 1, 2026

Applying the RatWalker System for Gait Analysis in a Genetic Rat Model of Parkinson's Disease
04:08

Applying the RatWalker System for Gait Analysis in a Genetic Rat Model of Parkinson's Disease

Published on: January 18, 2021

3.2K

Models of Parkinson's Disease Patient Gait

James Alexander Hughes, Sheridan Houghten, Joseph Alexander Brown

    IEEE Journal of Biomedical and Health Informatics
    |December 25, 2019
    PubMed

    Abstract:

    Parkinson's Disease is a disorder with diagnostic symptoms that include a change to a walking gait. The disease is problematic to diagnose. An objective method of monitoring the gait of a patient is required to ensure the effectiveness of diagnosis and treatments. We examine the suitability of Extreme Gradient Boosting (XGBoost) and Artificial Neural Network (ANN) Models compared to Symbolic Regression (SR) using genetic programming that was demonstrated to be successful in previous works on gait. The XGBoost and ANN models are found to out-perform SR, but the SR model is more human explainable.

    More Related Videos

    Gait Analysis of Age-dependent Motor Impairments in Mice with Neurodegeneration
    07:46

    Gait Analysis of Age-dependent Motor Impairments in Mice with Neurodegeneration

    Published on: June 18, 2018

    12.4K
    Asymmetric Walkway: A Novel Behavioral Assay for Studying Asymmetric Locomotion
    08:19

    Asymmetric Walkway: A Novel Behavioral Assay for Studying Asymmetric Locomotion

    Published on: January 15, 2016

    9.2K

    Related Experiment Videos

    Last Updated: Jan 1, 2026

    Applying the RatWalker System for Gait Analysis in a Genetic Rat Model of Parkinson's Disease
    04:08

    Applying the RatWalker System for Gait Analysis in a Genetic Rat Model of Parkinson's Disease

    Published on: January 18, 2021

    3.2K
    Gait Analysis of Age-dependent Motor Impairments in Mice with Neurodegeneration
    07:46

    Gait Analysis of Age-dependent Motor Impairments in Mice with Neurodegeneration

    Published on: June 18, 2018

    12.4K
    Asymmetric Walkway: A Novel Behavioral Assay for Studying Asymmetric Locomotion
    08:19

    Asymmetric Walkway: A Novel Behavioral Assay for Studying Asymmetric Locomotion

    Published on: January 15, 2016

    9.2K

    Related Concept Videos

    Parkinson's Disease: Overview01:15

    Parkinson's Disease: Overview

    1.6K
    Neurodegenerative disorders are progressive diseases that cause irreversible damage and loss to neurons in specific brain areas. Examples of these disorders include Parkinson's disease, Alzheimer's disease, Multiple Sclerosis (MS), and Amyotrophic Lateral Sclerosis (ALS). These disorders share characteristics such as proteinopathies, selective neuronal vulnerability, and a complex interplay between genetic and environmental factors. The primary therapeutic goal for these conditions is...
    1.6K
    Parkinson's Disease: Treatment01:24

    Parkinson's Disease: Treatment

    890
    Neurodegenerative disorders, such as Parkinson's Disease (PD), involve the gradual and irreversible destruction of neurons in particular brain areas. These disorders exhibit standard features like proteinopathies, selective vulnerability of some neurons, and an interaction of intrinsic properties, genetics, and environmental influences in neural injury.
    Parkinson's Disease is primarily a result of the loss of dopaminergic neurons in the substantia nigra pars compacta. The cornerstone of...
    890

    Articles linked to this work by shared authors, journal, and citation graph.

    Freezing of gait in Parkinson's disease: Classification using computational intelligence.

    Bio Systems·2023

    All lockdowns are not equal: Reducing epidemic impact through evolutionary computation.

    Bio Systems·2023

    Effective decoders for DNA codes.

    Bio Systems·2021

    Is Human Walking a Network Medicine Problem? An Analysis Using Symbolic Regression Models with Genetic Programming.

    Computer methods and programs in biomedicine·2021

    A centrality based multi-objective approach to disease gene association.

    Bio Systems·2020

    Lossy Compression of Quality Values in Sequencing Data.

    IEEE/ACM transactions on computational biology and bioinformatics·2019

    NSSGRN: Network Structure Selection Method for Gene Regulatory Network Construction.

    IEEE journal of biomedical and health informatics·2026

    Camera-Seismocardiography Based Cardiac Triggering for Magnetic Resonance Imaging: A Prospective Study.

    IEEE journal of biomedical and health informatics·2026

    MultiFPE: Multi-Representation Fusion Network for Facial Palsy Evaluation in Facial Videos.

    IEEE journal of biomedical and health informatics·2026

    Aging and Postural Changes Influence the Agreement Between Pulse Rate Variability and Heart Rate Variability.

    IEEE journal of biomedical and health informatics·2026

    DSTransformer: A Dual-Scale Transformer Framework for Zero-Shot Blood Glucose Prediction via Domain Generalization.

    IEEE journal of biomedical and health informatics·2026

    MobileSleepNet: A Deployment-Oriented Framework for Sleep Staging on Mobile Devices.

    IEEE journal of biomedical and health informatics·2026

    Characterization of pulmonary embolism events in patients with suspected pneumonia.

    Internal and emergency medicine·2026

    An anesthesia-integrated model for predicting postoperative urinary retention after transurethral resection of the prostate: A retrospective cohort study.

    The Journal of international medical research·2026

    Comparison of lower urinary tract symptoms between incontinent males and females: An analysis of AUASS and its subdomains.

    Urologia·2026

    Admission Clinical Features and Mean Values From Initial Bedside Noninvasive Monitoring for Predicting 3-Month Unfavorable Outcome After Traumatic Brain Injury: A Single-Center Retrospective Study With Temporal Validation.

    The Journal of craniofacial surgery·2026

    Validation of the Turkish version of the ANDROTEST for detecting male hypogonadism in patients with sexual dysfunction.

    Sexual medicine·2026

    Treatment of Severe Obstructive Sleep Apnea With a Domestic Implantable Hypoglossal Nerve Stimulator: A Case Report.

    World journal of otorhinolaryngology - head and neck surgery·2026
    See all related articles
    JoVE
    x logofacebook logolinkedin logoyoutube logo
    ABOUT JoVE
    OverviewLeadershipBlogJoVE Help Center
    AUTHORS
    Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
    LIBRARIANS
    TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
    RESEARCH
    JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
    EDUCATION
    JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
    Terms & Conditions of Use
    Privacy Policy
    Policies
    Jove
    Visualize
    Contact Us