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Updated: Jan 1, 2026
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Multimodal Volumetric Retinal Imaging by Oblique Scanning Laser Ophthalmoscopy oSLO and Optical Coherence Tomography OCT
Published on: August 4, 2018
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Generalized simultaneous multi-orientation 2D imaging
Nikolai J Mickevicius1, Andrew S Nencka2, Eric S Paulson1,2
1Department of Radiation Oncology, Medical College of Wisconsin, Milwaukee, WI, USA.
Magnetic Resonance in Medicine
|December 25, 2019
Summary
This study introduces a new framework for simultaneous multi-orientation (SMO) imaging, improving MR-guided therapy motion monitoring. The method enables faster imaging with more slices, enhancing temporal resolution for better real-time tracking.
Area of Science:
- Magnetic Resonance Imaging
- Medical Physics
- Image Acquisition
Background:
- Precise motion monitoring during MR-guided therapies requires flexible slice prescription.
- Increasing slice count for spatial coverage in 2D cine imaging often compromises temporal resolution.
Purpose of the Study:
- To describe a novel framework for simultaneous acquisition of multiple, arbitrarily oriented MRI slices.
- To enable higher frame rates for improved motion monitoring in MR-guided therapies.
Main Methods:
- Developed a framework to calculate zeroth gradient moments for sequentially excited slices with multiple orientations.
- Acquired data in phantom and in vivo (head/neck, abdomen) using the proposed method.
- Implemented in-plane acceleration for rapid imaging of moving objects.
Main Results:
- Successfully obtained arbitrarily rotated, simultaneous multi-orientation (SMO) images in phantom and in vivo.
- Demonstrated the capability for rapid imaging of physiological motion using SMO with acceleration.
Conclusions:
- The generalized SMO imaging framework is technically feasible.
- This approach shows significant promise for advancing motion monitoring in MR-guided therapies.
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