The association between anxiety and depression with 25(OH)D and thyroid stimulating hormone levels

To evaluate the relationships between the serum levels of these parameters and mood disorders, including depression and anxiety.

One hundred and fifty patients (77 with anxiety and 73 with depression), aged 18 to 79 years old, who were referred to the Neuro Psychiatry Clinic of Uskudar University in Istanbul, Turkey were included in this study from June 2018 to December 2018. According to the Beck Anxiety Inventory and Beck Depression Inventory II results, the anxiety patients met the mild and moderate anxiety criteria and the depression patients met the moderate and severe depression criteria, respectively. Venous blood samples were collected after overnight fasting, and the 25(OH)D and thyroid stimulating hormone (TSH) levels were measured.

The data showed a significantly higher TSH level in the females when compared to their male counterparts in the severe depression subgroup (p=0.011).

A serum TSH evaluation may be considered as a useful biochemical marker for more efficient depression management.