Methanesulfinylation of Benzyl Halides with Dimethyl Sulfoxide
Duo Fu1, Jun Dong1, Hongguang Du1
1State Key Laboratory of Chemical Resource Engineering, Department of Organic Chemistry, College of Chemistry , Beijing University of Chemical Technology , Beijing 100029 , People's Republic of China.
Abstract:
A phenyltrimethylammonium tribromide-mediated nucleophilic substitution/oxygen transformation reaction of benzyl halides with DMSO has been developed. In this transition-metal-free reaction, DMSO acts as not only a solvent but also a "S(O)Me" source, thus providing a convenient method for the efficient and direct synthesis of various benzyl methyl sulfoxides.
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