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Updated: Jan 1, 2026

A Mouse Distraction Osteogenesis Model
Published on: November 14, 2018
The Effect of Photobiomodulation on Distraction Osteogenesis
Sarvin Sarmadi1, Behrad Tanbakuchi1, Arian Hesam Arefi2
1Department of Orthodontics, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran.
Abstract:
Distraction osteogenesis (DO) is a surgical procedure to increase bone height in different body parts. DO includes a surgical incision, wherein the bone is cut and a device is installed for further separation of the two ends by gradual unscrewing of the device screw. New bone gradually forms and fills the gap, and the bone height increases as such. Photobiomodulation (PBM) or low-level laser therapy (LLLT) enhances the formation of soft and hard tissue such as bone and can, therefore, accelerate the process of DO and shorten the duration of different surgical phases of DO such as latency, activation, and consolidation. Different laser types with variable exposure settings and protocols have been used for this purpose. The gallium-aluminum-arsenide (GaAlAs) diode laser is the most commonly used laser type for LLLT. This study reviews 18 published articles on the effects of LLLT on DO and summarizes their findings to further elucidate this topic.

