Endoscopic resection of sinonasal malignancies

Area of Science:

• Otolaryngology
• Surgical Oncology
• Neurosurgery

Background:

• Sinonasal cancers present unique challenges for surgical management.
• Traditional open approaches can lead to significant morbidity.
• Endoscopic resection has emerged as a less invasive alternative.

Purpose of the Study:

• To evaluate the outcomes of endoscopic resection for sinonasal cancer.
• To compare pure endonasal endoscopic approach with endoscopic-assisted approach.
• To assess survival rates and surgical complications.

Main Methods:

• Retrospective review of 239 patients with sinonasal cancer.
• Patients treated with either pure endonasal endoscopic or endoscopic-assisted resection.
• Outcomes analyzed included survival and surgical complications.

Main Results:

• Overall, 239 patients were included with a median follow-up of 46.6 months.
• 167 (70%) underwent pure endonasal endoscopic approach, 72 (30%) had endoscopic-assisted approach.
• Postoperative cerebrospinal fluid (CSF) leakage occurred in 5.9% of patients. Negative margins were achieved in 87.4% with no significant difference between groups. Survival outcomes were also similar between the groups.

Conclusions:

• Endoscopic resection is an oncologically sound alternative for carefully selected sinonasal cancer patients.
• The procedure is associated with acceptable morbidity and low complication rates.
• This approach may reduce the need for more invasive open surgeries.