[Structure design and testing of drug micro-jetting multifunctional system]

Area of Science:

• Biomedical Engineering
• Pharmaceutical Engineering
• Materials Science

Background:

• Biomedical research requires precise methods for drug delivery systems and material coatings.
• Existing technologies may lack the versatility needed for diverse applications like microcapsule preparation and alloy coating.

Purpose of the Study:

• To design and validate a multifunctional drug micro-jetting system.
• To integrate piezoelectric micro-jetting with electromechanical and control technologies.
• To establish a versatile platform for biomedical and pharmaceutical engineering research.

Main Methods:

• The system was designed based on modular concepts, incorporating a piezoelectric micro-jetting subsystem, motion platform, and automated controls.
• The system's functionality was tested through experimental preparations.
• Key experiments included amoxicillin microcapsule preparation, titanium alloy drug-loaded coating, and balloon electrode coating.

Main Results:

• The developed drug micro-jetting system demonstrated versatility, rationality, and feasibility across multiple applications.
• Successful preparation of amoxicillin microcapsules was achieved.
• Drug-loaded coatings on titanium alloy and balloon electrodes were successfully prepared.

Conclusions:

• The designed drug micro-jetting system serves as a viable platform for advanced biomedical and pharmaceutical research.
• The integration of piezoelectric technology offers precise control for micro-particulate preparation and material coating.
• This system supports multi-disciplinary research in areas such as biomedical and pharmaceutical engineering.