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Related Experiment Video

Updated: Jan 1, 2026

Reduction of Iatrogenic Atrial Septal Defects with an Anterior and Inferior Transseptal Puncture Site when Operating the Cryoballoon Ablation Catheter

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Ab Interno Trabeculotomy: Key Prognostic Factors.

Arvi-Matti Kuusniemi¹, Nina Lindbohm, Pasi Allinen

¹Helsinki University Hospital, Helsinki, Finland.

Journal of Glaucoma

|December 27, 2019

Summary

Previous selective laser trabeculoplasty (SLT) and longer axial length (AL) over 23.82 mm are linked to reduced success after ab interno trabeculotomy (AbIT) in glaucoma patients. These factors predict a decreased survival rate for the AbIT procedure.

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Area of Science:

Ophthalmology
Glaucoma Surgery
Surgical Outcomes

Background:

Ab interno trabeculotomy (AbIT) using a Trabectome is a surgical option for open-angle glaucoma.
Predicting the success of AbIT is crucial for patient management and surgical planning.

Purpose of the Study:

To identify preoperative factors that predict the success of ab interno trabeculotomy (AbIT) performed with a Trabectome.

Main Methods:

A retrospective, single-center cohort study analyzed 72 eyes of 67 patients with primary open-angle or exfoliation glaucoma.
Patients underwent AbIT with preoperative intraocular pressure (IOP) ≥18 mmHg and were followed for at least 1 year.
Success was defined by a ≥20% IOP reduction or decreased medication without IOP rise or further surgery.

Main Results:

A history of prior selective laser trabeculoplasty (SLT) and a preoperative axial length (AL) exceeding 23.82 mm were significantly associated with decreased AbIT survival.
Preoperative SLT had a hazard ratio of 2.99 (P=0.013), and AL > 23.82 mm had a hazard ratio of 5.75 (P<0.001).

Conclusions:

Previous SLT treatment and longer axial length (>23.82 mm) are key preoperative factors negatively impacting the long-term success of AbIT.
These findings aid in patient selection and expectation setting for AbIT surgery in glaucoma.