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Updated: Jan 1, 2026

Multicolor Fluorescence Detection for Droplet Microfluidics Using Optical Fibers
Published on: May 5, 2016
Detection of the Crystallization Process of Paracetamol with a Multi-Mode Optical Fiber in a Reflective Configuration
Liliana Soares1,2, Susana Novais1, António Ferreira3
1INESC TEC-Institute for Systems and Computer Engineering, Technology and Science, Rua do Campo Alegre 687, 4169-007 Porto, Portugal.
Abstract:
A configuration of a refractometer sensor is described with the aim of optically detecting the crystallization process of paracetamol. The developed sensing head is based on a conventional cleaved multi-mode fiber. The fiber tip sensor structure was submitted to contact with the liquid of interest (paracetamol fully dissolved in 40% v/v of ethanol/water) and the crystallization process of paracetamol, induced with continued exposure to air, was monitored in real time.

