Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Gas Chromatography: Types of Detectors-II01:19

Gas Chromatography: Types of Detectors-II

1.0K
In gas chromatography, different detectors are employed to meet specific analytical needs. These detectors are often categorized based on their detection mechanisms and the types of compounds they are best suited to analyze. Thermal Conductivity Detectors (TCD), Flame Ionization Detectors (FID), and Electron Capture Detectors (ECD) represent common categories, each with unique operating principles and applications. However, beyond these, several other detectors are designed for more specialized...
1.0K
High-Performance Liquid Chromatography: Types of Detectors01:15

High-Performance Liquid Chromatography: Types of Detectors

1.4K
The role of the detectors in High-Performance Liquid Chromatography (HPLC) is to analyze the solutes as they exit from the chromatographic column. The detector recognizes the solute's property and generates corresponding electrical signals, which are converted into a readable graph of the detector's response versus elution time called a chromatogram at the computer. There are several types of HPLC detectors, each with its own advantages and limitations, depending on the analyte...
1.4K
Gas Chromatography: Overview of Detectors01:13

Gas Chromatography: Overview of Detectors

1.7K
Detectors in gas chromatography (GC) help identify and quantify the components of a mixture by translating chemical properties into measurable signals, which are displayed on a chromatogram. Detectors can be categorized into two main types: destructive and non-destructive.
A non-destructive detector allows a sample to be analyzed without altering or consuming it, meaning the sample can be collected after detection for further analysis. Examples include thermal conductivity detectors and...
1.7K
Gas Chromatography: Types of Detectors-I01:21

Gas Chromatography: Types of Detectors-I

1.3K
There are different types of detectors used in gas chromatography, each with its own specific properties that make it suitable for detecting certain types of analytes. The most commonly used detectors in GC are thermal conductivity detector (TCD), flame ionization detector (FID), and electron capture detector (ECD).
TCD is the earliest and most widely used detector that operates by measuring the changes in the thermal conductivity of the carrier gas. When a sample compound enters the detector,...
1.3K
Gas Chromatography–Mass Spectrometry (GC–MS)01:14

Gas Chromatography–Mass Spectrometry (GC–MS)

6.3K
Gas chromatography–mass spectrometry (GC–MS) is the combination of analytical techniques of gas chromatography and mass spectrometry in a single instrument for analyzing a mixture of compounds. The gas chromatograph separates the compounds in the mixture, and the mass spectrometer analyzes each compound separately to determine the molecular masses and molecular structures.
A gas chromatograph consists of a long, narrow capillary column with a polysiloxane coating on the inner wall....
6.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Smart and Flexible Optical Solar Reflectors for Passive Radiative Cooling Regulation in Space Using a W:VO<sub>2</sub> Metasurface.

Nanophotonics (Berlin, Germany)·2026
Same author

A novel signal processing approach enabled by machine learning for the detection and identification of chemical warfare agent simulants using a GC-QEPAS system.

Forensic sciences research·2025
Same author

Machine Learning-Driven Data Fusion of Chromatograms, Plasmagrams, and IR Spectra of Chemical Compounds of Forensic Interest.

ACS omega·2025
Same author

VO<sub>2</sub> metasurface smart thermal emitter with high visual transparency for passive radiative cooling regulation in space and terrestrial applications.

Nanophotonics (Berlin, Germany)·2024
Same author

Lightweight Gas Sensor Based on MEMS Pre-Concentration and Infrared Absorption Spectroscopy Inside a Hollow Fiber.

Sensors (Basel, Switzerland)·2023
Same author

Compact GC-QEPAS for On-Site Analysis of Chemical Threats.

Sensors (Basel, Switzerland)·2023

Related Experiment Video

Updated: Jan 1, 2026

Quantitative Detection of Trace Explosive Vapors by Programmed Temperature Desorption Gas Chromatography-Electron Capture Detector
07:57

Quantitative Detection of Trace Explosive Vapors by Programmed Temperature Desorption Gas Chromatography-Electron Capture Detector

Published on: July 25, 2014

20.3K

A MEMS-Enabled Deployable Trace Chemical Sensor Based on Fast Gas-Chromatography and Quartz Enhanced Photoacousic

Stefano Zampolli1, Sandro Mengali2, Nicola Liberatore2

  • 1Institute for Microelectronics and Microsystems, Italian National Research Council CNR-IMM, 40129 Bologna, Italy.

Sensors (Basel, Switzerland)
|December 28, 2019
PubMed
Summary

A portable chemical sensor detects hazardous vapors using a two-stage pre-concentration system, fast gas chromatography (FAST-GC), and quartz-enhanced photoacoustic spectroscopy (QEPAS). This integrated system offers rapid, selective detection for real-world applications.

Keywords:
CBRNMEMS GCQEPASforensicsafety and security

More Related Videos

A Filter-based Surface Enhanced Raman Spectroscopic Assay for Rapid Detection of Chemical Contaminants
08:13

A Filter-based Surface Enhanced Raman Spectroscopic Assay for Rapid Detection of Chemical Contaminants

Published on: February 19, 2016

9.7K
Performing In Situ Closed-Cell Gas Reactions in the Transmission Electron Microscope
14:21

Performing In Situ Closed-Cell Gas Reactions in the Transmission Electron Microscope

Published on: July 24, 2021

4.4K

Related Experiment Videos

Last Updated: Jan 1, 2026

Quantitative Detection of Trace Explosive Vapors by Programmed Temperature Desorption Gas Chromatography-Electron Capture Detector
07:57

Quantitative Detection of Trace Explosive Vapors by Programmed Temperature Desorption Gas Chromatography-Electron Capture Detector

Published on: July 25, 2014

20.3K
A Filter-based Surface Enhanced Raman Spectroscopic Assay for Rapid Detection of Chemical Contaminants
08:13

A Filter-based Surface Enhanced Raman Spectroscopic Assay for Rapid Detection of Chemical Contaminants

Published on: February 19, 2016

9.7K
Performing In Situ Closed-Cell Gas Reactions in the Transmission Electron Microscope
14:21

Performing In Situ Closed-Cell Gas Reactions in the Transmission Electron Microscope

Published on: July 24, 2021

4.4K

Area of Science:

  • Analytical Chemistry
  • Sensor Technology
  • Spectroscopy

Background:

  • Hazardous vapor detection at trace levels is critical for safety and environmental monitoring.
  • Existing portable sensors often lack the selectivity and sensitivity required for complex environments.
  • Miniaturization of analytical instrumentation is essential for field deployment, particularly on robotic platforms.

Purpose of the Study:

  • To develop and demonstrate a portable, selective chemical sensor for hazardous vapors.
  • To integrate a Micro-Electro-Mechanical-System (MEMS) based fast gas-chromatographic (FAST-GC) system with a miniaturized quartz-enhanced photoacoustic spectroscopy (QEPAS) detector.
  • To enable real-world analyses in challenging environments with rapid response times.

Main Methods:

  • A two-stage purge and trap vapor pre-concentration system was employed.
  • A MEMS-based FAST-GC separation column was utilized for chemical separation.
  • A miniaturized QEPAS detector was integrated downstream of the GC column for detection.

Main Results:

  • The integrated GC/QEPAS sensor system achieved two-dimensional selectivity by combining GC retention time and QEPAS spectral information.
  • The sensor was designed for ruggedness and suitability for deployment on unmanned robotic ground vehicles.
  • This study represents the first demonstration of a miniaturized QEPAS device as a detector for FAST-GC, enabling analyses in dirty environments within minutes.

Conclusions:

  • The developed portable GC/QEPAS sensor offers a promising solution for selective hazardous vapor detection.
  • The system's miniaturization and rugged design make it suitable for field applications and robotic deployment.
  • The integration of FAST-GC and QEPAS provides a powerful analytical tool for rapid, real-world chemical sensing.