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A microbiological study of acute maxillary sinusitis in Bloemfontein
J Snyman1, A J Claassen, P L Botha
1Department of Otorhinolaryngology, University of the Orange Free State, Bloemfontein.
Summary
This study investigated acute maxillary sinusitis, finding that anaerobic bacteria were common. Erythromycin and chloromycetin effectively treated aerobic infections, while metronidazole was successful for anaerobic sinusitis.
Area of Science:
- Otolaryngology
- Microbiology
- Infectious Diseases
Background:
- Acute maxillary sinusitis is a common condition.
- Microbial etiology plays a crucial role in sinusitis pathogenesis.
- Understanding causative agents and their antibiotic sensitivities is key for effective treatment.
Purpose of the Study:
- To identify the microbiological spectrum of acute maxillary sinusitis.
- To determine antibiotic sensitivities of isolated pathogens.
- To evaluate treatment efficacy based on microbial findings.
Main Methods:
- Microbiological analysis of samples from 26 patients with acute maxillary sinusitis.
- Antibiotic sensitivity testing was performed on isolated microorganisms.
- Therapeutic outcomes were assessed for different antibiotic regimens.
Main Results:
- Positive cultures were obtained in 23 out of 26 patients (88.5%).
- Anaerobic bacteria were identified in 13 patients (50%).
- Haemophilus influenzae was prevalent in beta-lactamase non-producing strains. Erythromycin and chloromycetin showed equal efficacy in aerobic cases; metronidazole was effective in all anaerobic cases.
Conclusions:
- Anaerobic bacteria are significant contributors to acute maxillary sinusitis.
- Tailored antibiotic therapy based on microbiological findings improves treatment outcomes.
- Specific antibiotics like erythromycin, chloromycetin, and metronidazole demonstrate targeted efficacy.