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A new approach to accelerate readout segmented EPI with compressed sensing
Patrick Alexander Liebig1,2,3, Robin Martin Heidemann2, Bernhard Hensel1
1Center of Medical Physics and Biomedical Engineering, Friedrich-Alexander-University Erlangen-Nürnberg, Erlangen, Germany.
Magnetic Resonance in Medicine
|December 28, 2019
Summary
Variable Segment (VASE) RESOLVE significantly reduces scan times for high-resolution diffusion-weighted imaging. This new method halves acquisition time compared to existing techniques, improving image quality and signal-to-noise ratio.
Area of Science:
- Magnetic Resonance Imaging
- Image Acquisition Techniques
Background:
- High-resolution diffusion-weighted imaging (DWI) faces challenges from susceptibility-induced distortions and blurring.
- Segmented acquisition methods like RESOLVE (readout segmentation of long and variable echo-trains) improve DWI quality but increase scan time.
- Readout (RO) partial Fourier and simultaneous multi-slice (SMS) methods can shorten RESOLVE scan times.
Purpose of the Study:
- Introduce Variable Segment (VASE) RESOLVE, a novel approach to further accelerate image acquisition in segmented DWI.
- To reduce scan time in readout-segmented echo-planar imaging (EPI) acquisitions.
Main Methods:
- Adjusted phase evolution and effective echo-spacing to prevent segment boundary discontinuities.
- Employed higher undersampling factors and increased outer segment widths in k-space sampling.
- Utilized compressed sensing reconstruction techniques enabled by randomized sampling.
Main Results:
- VASE RESOLVE acquisitions demonstrated lower Root Mean Square (RMS) errors compared to standard reconstructions.
- In vivo VASE RESOLVE images exhibited a higher apparent signal-to-noise ratio.
- Achieved a twofold reduction in acquisition time compared to RESOLVE with SMS.
Conclusions:
- VASE RESOLVE offers a significant advancement in reducing acquisition time for readout-segmented DWI.
- This technique provides further acceleration beyond existing methods like SMS for RESOLVE acquisitions.
- The VASE RESOLVE method enhances image quality and efficiency in diffusion-weighted imaging.

