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Antidiabetic Properties of Curcumin II: Evidence from In Vivo Studies

Danja J Den Hartogh1,2, Alessandra Gabriel1, Evangelia Tsiani1,2

  • 1Department of Health Sciences, Brock University, St. Catharines, ON L2S 3A1, Canada.

Nutrients
|December 29, 2019
PubMed

Insights

Curcumin, found in turmeric, shows promise in treating type 2 diabetes mellitus (T2DM). This review summarizes in vivo studies on curcumin

Area of Science:

  • Metabolic disease research
  • Nutritional science
  • Pharmacology

Background:

  • Type 2 diabetes mellitus (T2DM) is a prevalent metabolic disorder.
  • Insulin resistance and hyperglycemia characterize T2DM.
  • Current treatments for T2DM have limitations, necessitating novel therapeutic strategies.

Purpose of the Study:

  • To review in vivo studies on the antidiabetic effects of curcumin.
  • To explore curcumin's potential as a therapeutic agent for T2DM.

Main Methods:

  • Literature review of in vivo studies.
  • Analysis of research on curcumin and curcuminoids.

Main Results:

  • Curcumin exhibits antioxidant, anti-inflammatory, and hepatoprotective properties.
  • Evidence suggests curcumin possesses antidiabetic effects.
  • Studies indicate potential benefits for insulin resistance and T2DM management.

Conclusions:

  • Curcumin demonstrates significant potential for managing T2DM.
  • Further research into curcumin's therapeutic applications is warranted.
Keywords:
animal studiescurcumincurcuminoidsdiabeteshuman studiesin vivoinsulin resistance

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