Nutritional Advancement in the Hospitalized Child After NPO: A Retrospective Cohort Study

Alina G Burek1,2, Tracey Liljestrom3,2, Kelsey Porada2

  • 1Children's Hospital of Wisconsin, Milwaukee, Wisconsin; and aburek@mcw.edu.

Hospital Pediatrics
|December 29, 2019
PubMed

Insights

Transitioning children to a regular diet after a nil per os (NPO) order may shorten hospital stays. Clear-liquid diets did not improve diet tolerance but were linked to longer lengths of stay (LOS).

Area of Science:

  • Pediatric Gastroenterology
  • Clinical Nutrition
  • Hospital Medicine

Background:

  • Clear-liquid diets are standard after nil per os (NPO) orders for pediatric acute gastrointestinal (GI) illnesses.
  • The efficacy of clear-liquid diets versus immediate regular diets post-NPO is not well-established.
  • Understanding optimal diet progression can impact patient outcomes and hospital resource utilization.

Purpose of the Study:

  • To compare outcomes of clear-liquid diet versus regular diet after NPO in pediatric patients.
  • To evaluate diet tolerance, pain, and length of stay (LOS) in children recovering from acute GI illness.

Main Methods:

  • Retrospective cohort study of 39 pediatric patients (ages 1-18) admitted for acute GI illness.
  • Patients received either a clear-liquid diet or a regular diet post-NPO order.
  • Exclusion criteria included complex medical needs, feeding disorders, or chronic GI conditions.

Main Results:

  • No significant differences in diet tolerance (emesis, pain scores, return to NPO) were observed between groups.
  • Patients on a clear-liquid diet experienced a significantly longer length of stay (LOS) post-diet initiation (P=.01).
  • This prolonged LOS remained significant after controlling for age, diagnosis, and pain scores (P=.03).

Conclusions:

  • Clear-liquid diets after NPO status are associated with longer LOS in children without improving diet tolerance.
  • Transitioning to a regular diet post-NPO may reduce LOS without adverse effects.
  • Clinical practice guidelines may benefit from reassessing routine clear-liquid diet progression.
Abstract

Related Concept Videos

Enteral Nutrition II: Nasointestinal and Gastrostomy Feeding01:15

Enteral Nutrition II: Nasointestinal and Gastrostomy Feeding

Enteral nutrition encompasses various methods of delivering nutrition directly to the gastrointestinal (GI) tract, bypassing traditional oral intake. It is particularly beneficial for patients who cannot eat by mouth but have a functioning digestive system. Key methods include nasointestinal feeding, gastrostomy, and jejunostomy, each suited to different clinical scenarios based on the patient's needs and condition.
Nasointestinal Feeding
Nasointestinal feeding involves placing a tube...
707
Enteral Nutrition I: Orogastric and Nasogastric Feeding01:26

Enteral Nutrition I: Orogastric and Nasogastric Feeding

Enteral nutrition delivers nutrients directly to the stomach or small intestine through a tube. This method is appropriate for patients who cannot eat but still have a functioning digestive system. It is also beneficial for individuals with swallowing difficulties, anorexia, malabsorption, or those who have undergone gastrointestinal (GI) surgery.
Orogastric (OG) and nasogastric (NG) feeding are two standard methods used for enteral nutrition. Enteral nutrition is often preferred over...
1.1K
Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption01:23

Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption

Understanding the physiological differences in the pediatric population is crucial for effective pharmacotherapy. Neonates, infants, and children exhibit significant variations in gastric pH, gastric emptying time, intestinal transit time, and biliary function. These variations profoundly affect oral drug absorption, necessitating a nuanced approach to pediatric dosing.Neonates present with a unique physiological profile, having a gastric pH greater than 4 and faster and more irregular gastric...
191
Parentral Nutrition: Centeral and Peripheral Parental Nutrition01:27

Parentral Nutrition: Centeral and Peripheral Parental Nutrition

Parenteral Nutrition (PN) delivers essential nutrients directly into the bloodstream, bypassing the digestive system. It is commonly used for individuals with severe digestive disorders or conditions that prevent normal nutrient absorption.
PN can be administered through two primary routes:
1. Central Parenteral Nutrition (CPN):
CPN involves delivering a high concentration of nutrients through a large vein. This is typically achieved using a Peripherally Inserted Central Catheter (PICC) or,...
639
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy01:30

Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy

Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
576
Pharmacokinetics in Pediatric Patients: Drug Metabolism01:24

Pharmacokinetics in Pediatric Patients: Drug Metabolism

In pediatric care, understanding the nuances of hepatic drug metabolism is crucial, as it significantly differs from that of adults. This divergence is primarily due to the developmental stage of drug-metabolizing enzymes, which affects how medications are processed in the body. In neonates, for instance, the activity of Phase I enzymes—critical for the initial breakdown of drugs—is markedly reduced, functioning at just 20–40% of the levels seen in adults. This reduction poses...
152