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Preparation of graphene oxide incorporated monolithic chip based on deep eutectic solvents for solid phase extraction
Yan-Feng Shen1, Xue Zhang1, Chun-E Mo1
1Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics (Theranostics), School of Pharmacy, Tianjin Medical University, Tianjin, 300070, China.
Analytica Chimica Acta
|December 30, 2019
Summary
A novel graphene oxide (GO) monolithic chip was developed using deep eutectic solvents (DESs) for solid phase extraction (SPE). This GO-doped chip significantly enhances the recovery of polycyclic aromatic hydrocarbons, achieving over 90% efficiency.
Area of Science:
- Materials Science
- Analytical Chemistry
- Nanotechnology
Background:
- Solid phase extraction (SPE) is a crucial technique for sample purification and analyte enrichment.
- Graphene oxide (GO) possesses unique properties suitable for chromatographic applications.
- Deep eutectic solvents (DESs) offer tunable properties for material synthesis.
Purpose of the Study:
- To develop a novel monolithic chip for SPE incorporating graphene oxide (GO).
- To functionalize GO with p-aminostyrene (pAS) and covalently incorporate it into a polymer monolith.
- To evaluate the performance of the GO-doped monolithic chip for the extraction of polycyclic aromatic hydrocarbons (PAHs).
Main Methods:
- Synthesis of carboxylated GO modified with p-aminostyrene (pAS-COOH-GO).
- Covalent incorporation of pAS-COOH-GO into a poly(butyl methacrylate-co-ethylene glycol dimethyl methacrylate) monolithic chip using DESs.
- Characterization of the monolithic chip using nitrogen adsorption, SEM, and TEM.
- SPE of PAHs using the developed monolithic chip.
Main Results:
- A uniform pAS-COOH-GO incorporated monolithic chip with good permeability was successfully fabricated.
- The GO-doped monolithic chip demonstrated significantly enhanced SPE performance for PAHs compared to GO-free monoliths.
- Recoveries for all tested PAHs (phenanthrene, anthracene, fluoranthene, pyrene, benzo(a)anthracene, benzo(a) pyrene, dibenzo(a,h)anthracene, and inden(1,2,3,-cd)pyrene) exceeded 90%.
Conclusions:
- The developed GO-doped monolithic chip is effective for the SPE of PAHs.
- The incorporation of GO into the monolithic structure significantly improves extraction efficiency.
- This novel material offers a promising platform for advanced analytical applications.
