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A Case of an Adult Wilms Tumour in a Patient With Velocardiofacial Syndrome
Elizabeth Ferreira1, Mohammad Mohaghegh2, Siv Venkat2
1Department of Pathology, Max Rady College of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada.
Abstract:
Adult Wilms tumors (nephroblastomas) are exceedingly rare with less than 500 cases reported in the literature. To our knowledge, ours is the first reported case of a patient with velocardiofacial syndrome (Shprintzen syndrome) acquiring an adult Wilms tumor. The case highlights the possible role of chromosome 22q aberrations toward the pathogenesis of a subset of Wilms tumors.
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