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Published on: October 6, 2015
Malaria after chemotherapy for hematological malignancies.
M Igala1, L E Ledaga Lentombo1, L Kouégnigan Rerambiah2
1Université des sciences de la santé, Faculté de médecine et de pharmacie, Libreville, Gabon.
Cancer patients undergoing chemotherapy are at risk of infection. In Gabon, Plasmodium falciparum malaria is common and can complicate treatment, especially in those with hematological neoplasms.
Area of Science:
- Infectious diseases
- Hematology
- Oncology
Background:
- Cancer treatment, particularly for hematological malignancies, often compromises immune status, increasing infection susceptibility.
- Plasmodium falciparum malaria is endemic in Gabon, with significant prevalence in older children and adults.
Observation:
- This study details three cases of malaria in patients undergoing treatment for hematological neoplasms.
- Two of the reported malaria cases were severe, and one occurred in a patient with neutropenia.
Findings:
- Plasmodium falciparum malaria can occur and present severely in patients with hematological malignancies receiving chemotherapy.
- The parasite's involvement in post-chemotherapy fever for these patients is infrequently documented.
Implications:
- Highlights the importance of considering malaria in febrile patients with hematological neoplasms in endemic areas.
- Suggests a need for vigilance and prompt diagnosis of malaria in immunocompromised cancer patients in regions like Gabon.
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