Related Experiment Video
Updated: Sep 15, 2026

Acute Myocardial Infarction in Rats
Published on: February 16, 2011
McConnell's Sign Still Holds Its Value: A Lesson Learned from Two Cases
Tikal Kansara1, Fernando Quesada1, Hansang Park1
1Internal Medicine, New York Medical College - Metropolitan Hospital Center, New York, USA.
Abstract:
Acute pulmonary embolism (PE) can be potentially fatal if not diagnosed and treated early. Mortality in untreated cases can be as high as 30%. Atypical presentation and submassive PE can be missed due to subtle clinical features. Computerized tomography pulmonary angiogram is expensive, exposes to radiation and carries the risk of contrast nephropathy or anaphylactic reactions. On the contrary, McConnell's sign, which is a highly specific sign of PE, can be demonstrated at the bedside with a transthoracic echocardiogram (TTE). Here we discuss two cases where bedside TTE demonstrating McConnell's sign helped in the diagnosis and treatment of PE.
Related Concept Videos
Hindsight Biases
Multiple Comparison Tests
It would be easy to compare two samples using a significance alpha level of 0.05. In other words, there is only one sample pair to be compared. However, it would be difficult to identify a significantly different sample if the number...
Significance Testing: Overview
Mitral Stenosis II: Clinical features and Diagnostic Tests
McNemar's Test

