Collecting duct carcinoma of kidney: Masquerading as genitourinary tuberculosis - Lessons learnt
Mathisekaran T1, Deepak Raghavan2, Ranjanee Muthu3
1Apollo Main Hospital, Department Of Urology, 21, Greams Lane, Off Greams Road, Chennai, 600006, Tamilnadu, India.
Urology Case Reports
|January 1, 2020
Summary
Collecting duct carcinoma (CDC) mimicked genitourinary tuberculosis in a woman presenting with fever and loin pain. Surgical nephrectomy confirmed CDC, highlighting diagnostic challenges in rare kidney cancers.
Area of Science:
- Nephrology
- Urologic Oncology
- Diagnostic Imaging
Background:
- Collecting duct carcinoma (CDC) is a rare and aggressive renal malignancy.
- Genitourinary tuberculosis (GUTB) can present with similar nonspecific symptoms, posing a diagnostic challenge.
Observation:
- A 43-year-old woman presented with low-grade fever, anorexia, left loin pain, dyspnea, and hemoptysis.
- Initial evaluations suggested genitourinary tuberculosis or chronic granulomatous disease.
Findings:
- Extensive investigations were performed, leading to a referral to urology.
- Laparoscopic-assisted open left radical nephrectomy revealed the final diagnosis of collecting duct carcinoma.
Implications:
- This case underscores the importance of considering rare renal malignancies in the differential diagnosis of complex genitourinary presentations.
- Highlighting the diagnostic dilemma emphasizes the need for thorough evaluation and advanced imaging in atypical cases.
- The successful surgical management demonstrates a potential treatment pathway for localized collecting duct carcinoma.
Related Concept Videos
Pulmonary Tuberculosis III
831
Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
The first classification is based on the development of the disease, and it includes the following categories:
831
Renal Tubule and Collecting Duct
2.9K
The renal tubule is divided into three parts: the proximal convoluted tubule (PCT), the Loop of Henle (LOH), and the distal convoluted tubule (DCT).
Proximal Convoluted Tubule (PCT):
The PCT is the initial segment of the renal tubule, extending from the Bowman's capsule that encloses the glomerulus. Its convoluted structure and microvilli-lined cells increase the surface area for reabsorption. The PCT reabsorbs glucose, amino acids, sodium, and water from the filtrate, ensuring essential...
Proximal Convoluted Tubule (PCT):
The PCT is the initial segment of the renal tubule, extending from the Bowman's capsule that encloses the glomerulus. Its convoluted structure and microvilli-lined cells increase the surface area for reabsorption. The PCT reabsorbs glucose, amino acids, sodium, and water from the filtrate, ensuring essential...
2.9K
Pulmonary Tuberculosis II
1.3K
Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
1.3K
Pulmonary Tuberculosis V
493
Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
493
Pulmonary Tuberculosis I
770
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
770
Kidney Transplant II: Surgical Procedure
246
Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living...
246


