Related Experiment Video
Updated: Dec 31, 2025

In Vitro Model of Human Cutaneous Hypertrophic Scarring using Macromolecular Crowding
Published on: May 1, 2020
Diagnosis and Treatment of Keloids and Hypertrophic Scars-Japan Scar Workshop Consensus Document 2018
Rei Ogawa1, Sadanori Akita2, Satoshi Akaishi3
11Department of Plastic, Reconstructive and Aesthetic Surgery, Nippon Medical School, 1-1-5 Sendagi Bunkyo-ku, Tokyo, 113-8603 Japan.
Insights
Guidelines for diagnosing and treating keloids and hypertrophic scars are needed, especially for diverse ethnicities. The Japan Scar Workshop (JSW) developed the JSW Scar Scale (JSS) for objective assessment and treatment guidelines.
Area of Science:
- Dermatology
- Pathophysiology of fibrotic skin diseases
Background:
- Keloids and hypertrophic scars are common fibrotic skin conditions, particularly in Asian and African populations.
- Ethnic disparities exist in scar prevalence and severity, leading to varied diagnostic and treatment approaches globally.
- Lack of standardized guidelines results in inconsistent clinical management and outcomes.
Purpose of the Study:
- To introduce the Japan Scar Workshop (JSW) Scar Scale (JSS) for objective diagnosis and severity assessment of keloids and hypertrophic scars.
- To present consensus-based treatment guidelines for keloids and hypertrophic scars, simplifying strategy selection for clinicians.
- To provide a comprehensive resource for physicians worldwide managing these fibrotic skin conditions.
Main Methods:
- Development of the JSW Scar Scale (JSS) involving risk factor scoring for objective scar assessment.
- Formation of a committee with multidisciplinary experts to create consensus treatment guidelines.
- Compilation of a Consensus Document detailing diagnostic algorithms, treatment rationales, and site-specific protocols.
Main Results:
- The JSW Scar Scale (JSS) offers a simple, objective tool for diagnosing and grading keloids and hypertrophic scars.
- The Consensus Document provides clear, actionable treatment guidelines for various clinical settings.
- The guidelines cover differential diagnosis, general and site-specific treatment strategies, and underlying treatment rationales.
Conclusions:
- The JSW Scar Scale (JSS) and Consensus Document aim to standardize the diagnosis and treatment of keloids and hypertrophic scars.
- These tools are designed to assist clinicians, including those with less experience, in managing these conditions effectively.
- The initiative seeks to improve patient outcomes by providing evidence-based, globally applicable guidelines for fibrotic skin diseases.
Abstract:
There has been a long-standing need for guidelines on the diagnosis and treatment of keloids and hypertrophic scars that are based on an understanding of the pathomechanisms that underlie these skin fibrotic diseases. This is particularly true for clinicians who deal with Asian and African patients because these ethnicities are highly prone to these diseases. By contrast, Caucasians are less likely to develop keloids and hypertrophic scars, and if they do, the scars tend not to be severe. This ethnic disparity also means that countries vary in terms of their differential diagnostic algorithms. The lack of clear treatment guidelines also means that primary care physicians are currently applying a hotchpotch of treatments, with uneven outcomes. To overcome these issues, the Japan Scar Workshop (JSW) has created a tool that allows clinicians to objectively diagnose and distinguish between keloids, hypertrophic scars, and mature scars. This tool is called the JSW Scar Scale (JSS) and it involves scoring the risk factors of the individual patients and the affected areas. The tool is simple and easy to use. As a result, even physicians who are not accustomed to keloids and hypertrophic scars can easily diagnose them and judge their severity. The JSW has also established a committee that, in cooperation with outside experts in various fields, has prepared a Consensus Document on keloid and hypertrophic scar treatment guidelines. These guidelines are simple and will allow even inexperienced clinicians to choose the most appropriate treatment strategy. The Consensus Document is provided in this article. It describes (1) the diagnostic algorithm for pathological scars and how to differentiate them from clinically similar benign and malignant tumors, (2) the general treatment algorithms for keloids and hypertrophic scars at different medical facilities, (3) the rationale behind each treatment for keloids and hypertrophic scars, and (4) the body site-specific treatment protocols for these scars. We believe that this Consensus Document will be helpful for physicians from all over the world who treat keloids and hypertrophic scars.
Related Concept Videos
Skin Cancer
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Varicose Veins II: Diagnostic Studies and Interprofessional Care
Clinical Applications of Epidermal Stem Cells

