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[Strain dependency of immune reactions in the mouse]
1Institut für Medizinische Immunologie, Bereichs Medizin (Charité) Humboldt-Universität zu Berlin.
Abstract:
Using three models of immune reactions - the DTH-reaction, the GvH-reaction, and the modulation of immune reactions by histamine - we show that the strain-dependent variability between different inbred strains may exist not only on the quantitative but also on the qualitative level. For many problems it seems necessary to test the suitability of different mouse strains to avoid errors.