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Role of Frailty on Risk Stratification in Cardiac Surgery and Procedures
Samuele Baldasseroni1, Alessandra Pratesi2, Francesco Orso1
1Geriatric Medicine Unit, University of Florence and Azienda Ospedaliero-Universitaria Careggi, Florence, Italy.
Insights
The Comprehensive Geriatric Assessment (CGA) can improve predictions for older adults undergoing transcatheter aortic valve implantation (TAVI). This tool helps identify frailty and optimize treatment selection for better outcomes.
Area of Science:
- Geriatric Medicine
- Interventional Cardiology
- Cardiovascular Surgery
Background:
- Increasing number of elderly patients undergoing interventional cardiology procedures like TAVI.
- Higher perioperative risks, mortality, and disability in older adults compared to younger patients.
- Limitations of current specialist-oriented risk scores in capturing geriatric-specific outcomes.
Purpose of the Study:
- To introduce the Comprehensive Geriatric Assessment (CGA) as a tool for evaluating elderly patients for interventional cardiology.
- To improve prognostic accuracy beyond traditional outcomes, incorporating frailty-related factors.
- To aid physicians in determining the futility of interventions and optimizing TAVI candidate selection.
Main Methods:
- Development and application of a multidimensional diagnostic process (CGA).
- Focus on detecting frailty and assessing geriatric-specific outcomes (delirium, cognitive decline, institutionalization, functional status).
- Comparison with existing specialist-oriented surgical risk scores.
Main Results:
- CGA aims to enhance the prognostic ability of current risk scores for short and long-term mortality and disability.
- Provides clinical indications to identify futile interventional approaches.
- Potential to optimize the selection of TAVI candidates who will maximally benefit.
Conclusions:
- The CGA is a valuable geriatric tool for assessing frailty in older adults undergoing interventional cardiology.
- It improves risk prediction and aids in clinical decision-making for procedures like TAVI.
- Optimized patient selection using CGA can lead to better procedural outcomes and resource utilization.
Abstract:
The number of older people candidates for interventional cardiology, such as PCI but especially for transcatheter aortic valve implantation (TAVI) , would increase in the future. Generically, the surgical risk, the amount of complications in the perioperative period, mortality and severe disability remain significantly higher in the elderly than in younger. For this reason it's important to determine the indication for surgical intervention, using tools able to predict not only the classics outcome (length of stay, mortality), but also those more specifically geriatrics, correlate to frailty: delirium, cognitive deterioration, risk of institutionalization and decline in functional status. The majority of the most used surgical risks scores are often specialist-oriented and many variables are not considered. The need of a multidimensional diagnostic process, focused on detect frailty, in order to program a coordinated and integrated plan for treatment and long term follow up, led to the development of a specific geriatric tool: the Comprehensive Geriatric Assessment (CGA). The CGA has the aim to improve the prognostic ability of the current risk scores to capture short long term mortality and disability, and helping to resolve a crucial issue providing solid clinical indications to help physician in the definition of on interventional approach as futile. This tool will likely optimize the selection of TAVI older candidates could have the maximal benefit from the procedure.
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