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Optic disk size in ischemic optic neuropathy.

A M Mansour1, D Shoch, S Logani

  • 1Department of Ophthalmology, University of Texas Medical Branch, Galveston 77550.

American Journal of Ophthalmology
|November 15, 1988
PubMed
Summary
This summary is machine-generated.

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Fellow eyes of patients with non-arteritic anterior ischemic optic neuropathy exhibit a smaller optic disk horizontal diameter and area compared to controls. This suggests optic nerve fiber crowding may predispose individuals to optic neuropathy.

Area of Science:

  • Ophthalmology
  • Neuro-ophthalmology
  • Optic Neuropathy Research

Background:

  • Non-arteritic anterior ischemic optic neuropathy (NAION) is a leading cause of sudden, painless vision loss.
  • The pathophysiology of NAION is not fully understood, but risk factors are being investigated.
  • Optic disk morphology is a potential predisposing factor for NAION.

Purpose of the Study:

  • To investigate optic disk morphometric differences in fellow eyes of patients with unilateral NAION compared to healthy controls.
  • To determine if specific optic disk dimensions are associated with an increased risk of NAION.

Main Methods:

  • Measurement of horizontal and vertical optic disk diameters and disk area.
  • Comparison between fellow eyes of unilateral NAION patients and age- and sex-matched healthy control eyes.

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  • Statistical analysis to identify significant differences between groups.

    • Main Results:

    • Fellow eyes of NAION patients showed a significantly smaller horizontal disk diameter compared to vertical disk diameter (P < .05).
    • Both horizontal disk diameter and total disk area were significantly smaller in NAION fellow eyes than in control eyes (P < .05).
    • No significant difference was found in vertical disk diameters between the two groups.

    Conclusions:

    • A smaller optic disk area and horizontal shortening of the scleral canal may predispose individuals to NAION.
    • Optic nerve fiber crowding due to these morphometric characteristics could lead to circulatory compromise.
    • These findings highlight the role of optic disk anatomy in the development of non-arteritic anterior ischemic optic neuropathy.