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Related Concept Videos

Drug Dosing: Geriatric Patients01:15

Drug Dosing: Geriatric Patients

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Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
185
Pharmacodynamics in Geriatric Patients: Effects of Age01:27

Pharmacodynamics in Geriatric Patients: Effects of Age

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Age-related pharmacokinetic changes are extensively documented, but understanding age-related pharmacodynamic alterations is relatively limited. This knowledge gap can be partly attributed to the complexity of developing appropriate measures of drug responses compared to bioanalytical methods for determining drug concentrations.Most information regarding age-related differences in human pharmacodynamics originates from cross-sectional studies. However, these studies assume that observed mean...
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Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Excretion01:18

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Excretion

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In geriatric patients, renal physiology undergoes significant changes, including diminished renal blood flow and a lower glomerular filtration rate (GFR), leading to alterations in medication clearance. Drugs such as aminoglycoside antibiotics, lithium, and digoxin, which rely on glomerular filtration for removal from the body, particularly impact pharmacokinetics. These drugs tend to have slower clearance rates in older adults, necessitating careful dosage considerations.Evaluation of renal...
198
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution01:00

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution

164
Drug distribution in the human body is influenced by several factors, including plasma protein concentration, body composition, blood flow, tissue-protein concentration, and tissue fluid pH. Among these, changes in plasma protein concentration and body composition due to aging significantly affect how drugs are distributed within the body. Specifically, aging is associated with a decrease in albumin levels by about 10% and an increase in α1-acid glycoprotein levels. These alterations are...
164
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption01:22

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption

181
As individuals age, their body's physiology evolves, affecting drug pharmacokinetics. The most apparent changes occur in the gastrointestinal tract, where an increase in gastric pH, a delay in gastric emptying, and a reduction in gastrointestinal motility are observed. Remarkably, these changes do not substantially modify the absorption of orally administered drugs, particularly those absorbed via passive diffusion.Transdermal drug delivery emerges as a highly viable method for older adults due...
181
Erikson's Theory on Socioemotional Development during Adulthood01:27

Erikson's Theory on Socioemotional Development during Adulthood

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Erik Erikson's theory of psychosocial development outlines a series of stages through which individuals progress across the lifespan. Each stage involves a psychosocial conflict that significantly influences personal growth and well-being. Three key stages — intimacy versus isolation, generativity versus stagnation, and integrity versus despair — highlight the developmental challenges faced in adulthood.
Intimacy Versus Isolation in Early Adulthood
Individuals in early...
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Validation of a Psychosocial Intervention on Body Image in Older People: An Experimental Design
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Suicide in Older Adults.

Jeanne M Sorrell

    Journal of Psychosocial Nursing and Mental Health Services
    |January 3, 2020
    PubMed
    Summary

    Suicide among older adults is a serious issue requiring immediate attention from healthcare professionals. More research is needed on effective interventions to prevent late-life suicide and train clinicians to manage at-risk seniors.

    Area of Science:

    • Geriatric Psychiatry
    • Public Health
    • Nursing

    Background:

    • Late-life suicide presents a critical public health challenge.
    • Healthcare professionals require enhanced skills to address this issue.

    Purpose of the Study:

    • To highlight the urgent need for evidence-based suicide prevention strategies in older adults.
    • To emphasize the necessity of skilled healthcare professionals for intervention.

    Main Methods:

    • Literature review on geriatric suicide prevention.
    • Analysis of current healthcare professional training gaps.

    Main Results:

    • Limited availability of evidence-based interventions for late-life suicide.
    • Insufficient training for healthcare professionals in recognizing and managing suicide risk in older adults.

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    Assessment of Dependence in Activities of Daily Living Among Older Patients in an Acute Care Unit
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    Conclusions:

    • There is an urgent need for developing and implementing effective suicide prevention programs for the elderly.
    • Increased training and resources are essential for healthcare providers to support this vulnerable population.