Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Diabetes Mellitus: Type 2 and Gestational01:22

Diabetes Mellitus: Type 2 and Gestational

4.2K
Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
4.2K
Carbohydrate Metabolism01:36

Carbohydrate Metabolism

13.6K
Carbohydrates are polymers composed of molecules containing atoms of carbon, hydrogen and oxygen. One gram of carbohydrate can provide four kilo-calories of energy, which makes it the most efficient instant energy source.
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in...
13.6K
Diabetes Mellitus: Overview and Type I Subtype01:22

Diabetes Mellitus: Overview and Type I Subtype

4.7K
Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
4.7K
Pathophysiology of Diabetes01:20

Pathophysiology of Diabetes

3.0K
Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
3.0K
Diabetes: Management and Pharmacotherapy01:15

Diabetes: Management and Pharmacotherapy

804
The therapy for diabetes aims to alleviate hyperglycemia-related symptoms, prevent acute metabolic decompensation, and reduce chronic end-organ complications. Glycemic control is evaluated through short-term (self-monitoring, continuous glucose monitoring) and long-term (A1c, fructosamine) metrics, enabling near real-time tracking of blood glucose levels and reflecting glycemic control over specific time frames.
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
804
Chronic Pancreatitis II: Collaborative Care01:29

Chronic Pancreatitis II: Collaborative Care

264
The management of chronic pancreatitis is multifaceted, involving a comprehensive approach that includes thorough assessment, diagnostic testing, and a variety of management strategies.
Assessment:
264

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same authorSame journal

Outcomes of Metabolic and Bariatric Surgery Among Adolescents and Young Adults in Southern Louisiana.

Obesity surgery·2026
Same author

Preoperative Weight Loss: Helpful, Harmful or Irrelevant?

Obesity surgery·2026
Same author

Fertility and pregnancy knowledge and expectations among women with a history of metabolic bariatric surgery.

European journal of obstetrics, gynecology, and reproductive biology·2026
Same author

Cost-Effectiveness of Pharmacologic Therapies for Metabolic Dysfunction-Associated Steatohepatitis With Significant Fibrosis in the United States.

Diabetes, obesity & metabolism·2026
Same author

Increasing Obesity Severity Is Associated With Less Surgical Care in the United States.

Obesity (Silver Spring, Md.)·2026
Same author

Survodutide Once Weekly for the Treatment of Adults with Obesity.

The New England journal of medicine·2026
Same journal

Paired Editorials: Patient Satisfaction and Experience with Same-day Discharge After Laparoscopic Roux-en-Y Gastric Bypass: a Mixed-methods Study.

Obesity surgery·2026
Same journal

Better Prepared Than Surprised: A Call to Routinize Preparedness - Essentials of Pre- and Post-Operative Counselling on Psychological Challenges After Metabolic and Bariatric Surgery.

Obesity surgery·2026
Same journal

Associations Between Opioid Timing and Postoperative Desaturation Burden Following Metabolic Bariatric Surgery.

Obesity surgery·2026
Same journal

Cohort-Based Reference Percentiles for six BODY-Q Health-Related Quality of Life Scales after Metabolic and Bariatric Surgery.

Obesity surgery·2026
Same journal

Nutritional Status in Chinese Patients Undergoing Bariatric Surgery: A Retrospective 1-Year Follow-Up Study.

Obesity surgery·2026
See all related articles

Related Experiment Video

Updated: Dec 31, 2025

Isolation of Human Islets from Partially Pancreatectomized Patients
11:10

Isolation of Human Islets from Partially Pancreatectomized Patients

Published on: July 30, 2011

16.7K

Does Colectomy Improve Type 2 Diabetes?

Suriya Punchai1,2, Rickesha L Wilson1, Katherine M Meister1,3

  • 1Bariatric and Metabolic Institute, Department of General Surgery, Cleveland Clinic, 9500 Euclid Avenue, Desk M61, Cleveland, OH, 44195, USA.

Obesity Surgery
|January 4, 2020
PubMed
Summary
This summary is machine-generated.

Colectomy surgery for benign conditions did not significantly improve type 2 diabetes (T2DM) or body weight in patients. Long-term follow-up showed no lasting changes in glycemic control or BMI after the procedure.

Keywords:
BariatricBody weightColectomyColorectal diseaseType 2 diabetes mellitusWeight loss

More Related Videos

Duodenal-Jejunal Bypass Surgery in Diet-Induced Obese Diabetic Mice
08:50

Duodenal-Jejunal Bypass Surgery in Diet-Induced Obese Diabetic Mice

Published on: October 18, 2024

935
Sleeve Gastrectomy in Mice using Surgical Clips
05:16

Sleeve Gastrectomy in Mice using Surgical Clips

Published on: November 14, 2020

7.2K

Related Experiment Videos

Last Updated: Dec 31, 2025

Isolation of Human Islets from Partially Pancreatectomized Patients
11:10

Isolation of Human Islets from Partially Pancreatectomized Patients

Published on: July 30, 2011

16.7K
Duodenal-Jejunal Bypass Surgery in Diet-Induced Obese Diabetic Mice
08:50

Duodenal-Jejunal Bypass Surgery in Diet-Induced Obese Diabetic Mice

Published on: October 18, 2024

935
Sleeve Gastrectomy in Mice using Surgical Clips
05:16

Sleeve Gastrectomy in Mice using Surgical Clips

Published on: November 14, 2020

7.2K

Area of Science:

  • Gastroenterology
  • Endocrinology
  • Metabolic Surgery

Background:

  • Bariatric surgeries like gastrectomy and gastric bypass can improve type 2 diabetes (T2DM).
  • These improvements are thought to be linked to changes in gut hormones and the gut microbiome.
  • The impact of colorectal resections on T2DM remains less understood.

Purpose of the Study:

  • To investigate whether colectomy, a type of colorectal resection, leads to improvements in T2DM.
  • To analyze the long-term effects of colectomy on glycemic control and body weight in patients with T2DM.

Main Methods:

  • A retrospective study of 171 patients with T2DM who underwent colectomy for benign conditions.
  • Median follow-up of 3 years post-surgery.
  • Comparison of baseline and postoperative Body Mass Index (BMI) and glycated hemoglobin (HbA1c) levels, along with diabetes medication status.

Main Results:

  • No statistically significant differences were observed in median BMI (30.3 vs. 30.4 kg/m²) or median HbA1c (6.7% vs. 6.5%) between baseline and post-colectomy.
  • The proportion of patients requiring diabetes medications did not change significantly.
  • No significant differences in outcomes were found between different subtypes of colorectal resection.

Conclusions:

  • Colectomy for benign colorectal diseases is not associated with significant long-term improvements in glycemic control (HbA1c) or body weight (BMI).
  • The findings suggest that colorectal resections may not offer the same metabolic benefits for T2DM as some bariatric procedures.