Dynamic Delta-like1 expression in presomitic mesoderm cells during somite segmentation

Akari Takagi1, Akihiro Isomura2, Kumiko Yoshioka-Kobayashi1

  • 1Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto, 606-8507, Japan; Kyoto University Graduate School of Medicine, Kyoto, 606-8501, Japan.

Summary

Cell surface Delta-like1 (Dll1) protein oscillates during somitogenesis, regulating Hes7 gene oscillations. Slower Hes7 responses to Dll1 in the anterior presomitic mesoderm (PSM) control somite segmentation timing.

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