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Recurrent Pancreatitis in Children: Past, Present, and Future
1Division of Gastroenterology, Hepatology, and Nutrition, Children's Hospital of Pittsburgh, Pittsburgh, PA.
Journal of Pediatric Gastroenterology and Nutrition
|January 4, 2020
Summary
Childhood pancreatitis, including acute recurrent pancreatitis (ARP) and chronic pancreatitis (CP), is rising. Genetic and anatomical factors are key causes, impacting children
Area of Science:
- Pediatric Gastroenterology
- Hepatology
- Pancreatology
Background:
- Recurrent acute and chronic pancreatitis are increasingly diagnosed in children.
- Etiologies in children differ significantly from adults, primarily involving genetic and anatomical factors.
- Pediatric pancreatitis negatively affects quality of life and incurs high healthcare costs due to pain, hospitalizations, and procedures.
Purpose of the Study:
- To review recent advancements in understanding and managing pediatric acute recurrent pancreatitis (ARP) and chronic pancreatitis (CP).
- To highlight key discoveries that can improve physician care for children with these pancreatic conditions.
Main Methods:
- Comprehensive literature review of recent developments in pediatric ARP and CP.
- Synthesis of current knowledge on etiology, diagnosis, and treatment of childhood pancreatitis.
Main Results:
- Etiologies in children are predominantly genetic and anatomical, unlike adult-onset pancreatitis.
- Diagnostic methods are evolving, but treatment options remain limited.
- Pediatric pancreatitis leads to significant morbidity, including chronic abdominal pain and frequent healthcare utilization.
Conclusions:
- Recent discoveries offer new insights into pediatric pancreatitis.
- Physicians can leverage these findings to enhance care for affected children.
- Further research is needed to expand therapeutic strategies for pediatric ARP and CP.
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