Perinatal risk factors and reactive attachment disorder: A nationwide population-based study

Subina Upadhyaya1, Roshan Chudal1, Terhi Luntamo1

  • 1Department of Child Psychiatry, Research Centre for Child Psychiatry, University of Turku, Turku, Finland.

Insights

Low birthweight, preterm birth, and neonatal intensive care unit (NICU) admission are linked to reactive attachment disorder. These findings enhance understanding of developmental risks for this condition in children.

Area of Science:

  • Child Psychology
  • Developmental Pediatrics
  • Neonatal Care

Background:

  • Reactive attachment disorder (RAD) is a complex behavioral condition affecting young children.
  • Understanding the perinatal and obstetric factors associated with RAD is crucial for early intervention.

Purpose of the Study:

  • To investigate the relationship between various perinatal and obstetric risk factors and the development of reactive attachment disorder in children.
  • To identify specific risk factors that may predict RAD diagnosis in specialized services.

Main Methods:

  • A nested case-control study design was employed.
  • Data were sourced from Finnish national registers, including 614 cases of RAD and 2423 age- and sex-matched controls.
  • Conditional logistic regression analysis was used to assess associations between risk factors and RAD.

Main Results:

  • Low birthweight (<2500g) was associated with increased odds of RAD (OR 1.96).
  • Gestational age <32 weeks (OR 3.72), induced labor (OR 1.34), and neonatal intensive care unit (NICU) monitoring (OR 1.67) were linked to higher RAD odds.
  • Birthweight between 4000-4499g was associated with decreased odds of RAD (OR 0.49).

Conclusions:

  • Significant associations were found between low birthweight, preterm birth, and NICU admission and reactive attachment disorder.
  • These findings contribute to the existing knowledge base on the developmental origins of RAD.
  • Identifying these perinatal risk factors can inform clinical practice and support targeted prevention strategies.
Abstract

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