Related Experiment Video
Updated: Sep 3, 2026
Treating Low Back Pain in Failed Back Surgery Patients with Multicolumn-lead Spinal Cord Stimulation
Published on: June 26, 2018
Malfunctioning sufentanil intrathecal pain pump: a case report
Lindsay Warner1, Anna Branstad2, Lindsay Hunter Guevara3
1Department of Anesthesiology, Mayo Clinic, 200 1st SW, Rochester, MN, 55902, USA. warner.lindsay@mayo.edu.
Background:
Sufentanil is a potent opioid uncommonly used to manage pain and is rarely administered via an intrathecal pain pump system.
Case Presentation:
This case illustrates the use of intrathecal sufentanil in a 50-year-old Caucasian man for the management of chronic pain; however, the intrathecal drug delivery system experienced a malfunction which led to 1/100th output of the correct dosage. Interesting aspects of this case report include the uncommon choice of sufentanil use for an intrathecal drug delivery system, as well as the unusual pharmacokinetics of this drug. Specifically, this patient did not experience the major withdrawal that would be expected given significant under dosing of opioid, and this may be explained by the lipophilicity and context-sensitive half-times of sufentanil.
Conclusions:
Because of the absence of a clinically significant withdrawal in this case report, clinicians must be aware of relevant pharmacokinetic properties and unusual intrathecal drug delivery system technologies that influence a patient's response when device malfunction occurs.
