Related Experiment Video

Updated: Dec 31, 2025

Using Sniper-Cas9 to Minimize Off-target Effects of CRISPR-Cas9 Without the Loss of On-target Activity Via Directed Evolution
11:37

Using Sniper-Cas9 to Minimize Off-target Effects of CRISPR-Cas9 Without the Loss of On-target Activity Via Directed Evolution

Published on: February 26, 2019

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Engineering guide RNA to reduce the off-target effects of CRISPR

Jing Wu1, Hao Yin2

  • 1Department of Pathology, Medical Research Institute, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China; Frontier Science Center for Immunology and Metabolism, Wuhan University, 430071, China.

Journal of Genetics and Genomics = Yi Chuan Xue Bao
|January 7, 2020
PubMed

Keywords:
CRISPREngineered guide RNAGenome editingOff-target effects

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