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Updated: Dec 31, 2025

A Modified Surgical Technique for Kidney Transplantation in Mice
Published on: July 22, 2022
Ureterostomy as an alternative to ileal conduits in pediatric kidney transplantation
Aleah L Brubaker1, Hsi-Yang Wu2, Angela Lee1
1Division of Abdominal Transplantation, Department of Surgery, Stanford University, Palo Alto, California.
Introduction:
Urinary diversion in pediatric renal transplant candidates with bladders not amenable to primary reconstruction can be achieved by pre-transplant ileal conduit creation. We performed cutaneous ureterostomies to limit pre-transplant surgery, protect the peritoneum for dialysis, transplant patients sooner, and preserve ureter length for future surgical reconstruction.
Methods:
We compared four pediatric transplant recipients with ureterostomies to four recipients with ileal conduits from 2009 to 2017.
Results:
All patients with ileal conduits developed at least one urinary tract infection (UTI) within 1 year of transplant and three of four patients had recurrent UTIs within the first year. Two patients required ileal conduit revisions for redundant conduits and recurrent UTIs. Of the four ureterostomy patients, two patients had UTIs within one year of transplant. Two patients developed ureterostomy strictures requiring revision at the fascial level; one was associated with a UTI.
Conclusion:
In our small case series, ureterostomy allowed for a single operative intervention with preservation of ureter length for later reconstruction. Ureterostomy is safe and recurrent UTI may be lower in the ureterostomy group. Long-term evaluation of ureterostomy for urinary diversion in pediatric kidney transplant is warranted.
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