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[Effect of serum on the intra- and extracellular bactericidal capacity of neutrophils]
Arkhiv Patologii
|January 1, 1988
Abstract:
Donors' neutrophils are capable for inhibiting the growth of and killing staphylococci both intra- and extracellularly. In the absence of serum the rate of extracellular killing of microbes by donors' neutrophils is reaching that of killing phagocytized bacteria, while in the serum introduction the rate of intracellular killing overwhelms that of extracellular. Burnt patients' neutrophils fail to control the microbes multiplication either intra- or extracellularly without serum, while in combination with it both intra- and extracellular killing activity of neutrophils of the burnt sharply increases being superior to relevant combination of healthy subjects.