[Morphologic characteristics of the evolution of myocardial infarct after effective thrombolytic therapy]

Stroma and vessels which remain in the zone of myocardial infarction (MI) after thrombolytic therapy has restored impaired circulation during early hours of MI onset may produce foci of necrosis responsible for accelerated MI formation both in the periphery and centre of the foci. Hemorrhagic MI development can be related to microvascular and intramural vein spasms at early stages of the blood supply recovery. Fibrinoid necrosis of the wall and thrombosis of the lumen were observed in relevant vessels later on. These were associated with disturbed blood outflow from the infarction zone and hemorrhagic saturation of the interstice and cardiomyocytes.