Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Changes in Skin Color: Clinical Perspectives01:14

Changes in Skin Color: Clinical Perspectives

3.2K
The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
3.2K
Skin Cancer01:30

Skin Cancer

5.6K
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
5.6K
Skin Diseases and Disorders01:23

Skin Diseases and Disorders

5.1K
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
5.1K
Pigmentation01:19

Pigmentation

4.0K
The color of the skin is influenced by a number of pigments, including melanin, carotene, and hemoglobin. Recall that melanin is produced by cells called melanocytes, which are found scattered throughout the stratum basale of the epidermis. The melanin is transferred to the keratinocytes via melanosomes.
Melanin occurs in two primary forms: eumelanin that provides black and brown pigment and pheomelanin that provides red color. Dark-skinned individuals produce more melanin than those with pale...
4.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Safety Assessment of <i>Melaleuca alternifolia</i> (Tea Tree)-Derived Ingredients as Used in Cosmetics.

International journal of toxicology·2026
Same author

Safety Assessment of Radish Root - Derived Ingredients as Used in Cosmetics.

International journal of toxicology·2026
Same author

Amended Safety Assessment of Naturally-Sourced Clays as Used in Cosmetics.

International journal of toxicology·2026
Same author

Safety Assessment of Diatomaceous Earth as Used in Cosmetics.

International journal of toxicology·2026
Same author

Safety Assessment of Basic Yellow 87 as Used in Cosmetics.

International journal of toxicology·2026
Same author

Safety Assessment of Glycolactones as Used in Cosmetics.

International journal of toxicology·2026

Related Experiment Video

Updated: Dec 31, 2025

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
11:39

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

Published on: July 11, 2013

39.4K

Chronic Actinic Dermatitis Revisited.

Connie X Wang1, Donald V Belsito

  • 1From the *Vagelos College of Physicians and Surgeons †Department of Dermatology, Columbia University Medical Center, New York, NY.

Dermatitis : Contact, Atopic, Occupational, Drug
|January 7, 2020
PubMed
Summary

Chronic actinic dermatitis (CAD) affects a broader demographic than previously thought, including men and women of various skin types. Identifying specific allergens through photopatch testing is crucial for diagnosis and management.

More Related Videos

Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia
06:15

Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia

Published on: August 9, 2024

1.7K
Clinical Application of Intense Pulsed Light Therapy and Radio Frequency for Treatment of Ocular Surface Diseases
07:36

Clinical Application of Intense Pulsed Light Therapy and Radio Frequency for Treatment of Ocular Surface Diseases

Published on: July 3, 2025

547

Related Experiment Videos

Last Updated: Dec 31, 2025

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
11:39

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

Published on: July 11, 2013

39.4K
Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia
06:15

Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia

Published on: August 9, 2024

1.7K
Clinical Application of Intense Pulsed Light Therapy and Radio Frequency for Treatment of Ocular Surface Diseases
07:36

Clinical Application of Intense Pulsed Light Therapy and Radio Frequency for Treatment of Ocular Surface Diseases

Published on: July 3, 2025

547

Area of Science:

  • Dermatology
  • Allergology
  • Photodermatology

Background:

  • Chronic actinic dermatitis (CAD) traditionally affects older white men with plant allergies.
  • Recent evidence suggests evolving demographics in CAD patient populations.

Purpose of the Study:

  • Determine the frequency of CAD in patients with photosensitive eruptions.
  • Identify common allergens and photoallergens associated with CAD.

Main Methods:

  • Retrospective analysis of 246 patients undergoing photopatch testing (July 1994-June 2018).
  • Comparison of demographics and test results between CAD and non-CAD patients.

Main Results:

  • CAD was diagnosed in 7.7% of patients (19/246), with a male-to-female ratio of 1:1.7.
  • CAD patients showed higher rates of photocontact allergy/contact allergy to sesquiterpene lactone mix and fragrances.
  • Contact allergy to p-phenylenediamine was also prevalent in CAD patients.

Conclusions:

  • CAD presents across a wider demographic range, including both sexes and diverse skin types.
  • Phototesting and photopatch testing are recommended for suspected CAD cases.