Safety Assessment of Basic Yellow 87 as Used in Cosmetics
Christina L Burnett1, Wilma F Bergfeld2, Donald V Belsito2
1Cosmetic Ingredient Review Senior Scientific Analyst/Writer.
International Journal of Toxicology
|June 6, 2026
Summary
The Expert Panel for Cosmetic Ingredient Safety assessed Basic Yellow 87. They concluded this hair dye ingredient is safe for cosmetic use as currently practiced.
Area of Science:
- Cosmetic Science
- Toxicology
- Dermatology
Background:
- Basic Yellow 87 is utilized as a hair dye in cosmetic formulations.
- Assessing the safety of cosmetic ingredients is crucial for consumer protection.
Purpose of the Study:
- To evaluate the safety of Basic Yellow 87 for cosmetic applications, specifically as a hair dye.
- To review available toxicological and safety data pertaining to Basic Yellow 87.
Main Methods:
- The Expert Panel for Cosmetic Ingredient Safety (Panel) conducted a comprehensive review of existing data.
- Safety assessment involved analyzing scientific literature and relevant studies on Basic Yellow 87.
Main Results:
- The Panel examined various data points to determine the safety profile of Basic Yellow 87.
- The available evidence was critically assessed to understand potential risks associated with its use.
Conclusions:
- Basic Yellow 87 is deemed safe for use as a hair dye ingredient.
- The safety is established within the current practices of use and concentration levels detailed in the assessment.
Related Concept Videos
01:23Toxicity Testing in Animals
Toxicity tests in animals are grounded on two main assumptions: first, the effects observed in laboratory animals can be extrapolated to humans, especially when adjusted for body surface area; second, high-dose exposure in animals is essential to identify potential human hazards from lower doses. This is based on the quantal dose-response concept, which faces the challenge of extrapolating results from relatively few test animals to much larger human populations. For example, a 0.01% incidence...
01:26Toxic Reactions: Overview
When toxic substances penetrate the human body, they disseminate to various tissues, undergoing metabolic changes. This process yields reactive metabolites that may covalently bind with specific target molecules, resulting in toxicity.
Toxicity falls into two primary categories: local and systemic.
Local toxicity appears at the exposure site, such as protein denaturation caused by caustic substances.
In contrast, systemic toxicity requires the toxic agent's absorption and distribution,...
Toxicity falls into two primary categories: local and systemic.
Local toxicity appears at the exposure site, such as protein denaturation caused by caustic substances.
In contrast, systemic toxicity requires the toxic agent's absorption and distribution,...
01:30Assessment of Airway, Skin Color, and Use of Accessory Muscles
A thorough assessment of respiratory health is paramount in clinical settings to identify and manage respiratory distress and ensure adequate oxygenation. This article elaborates on the critical aspects of respiratory evaluation, including airway assessment, skin color examination, and the observation of accessory muscle use, which are integral to effectively diagnosing and managing patients with respiratory conditions.
Introduction
The initial evaluation of a patient's respiratory system...
Introduction
The initial evaluation of a patient's respiratory system...
01:26Physical Properties of Amines
Amines with low molecular weight are usually gaseous at room temperature, while those with high molecular weight are liquid or solids in nature. Usually, low molecular weight amines have a rotten fish-like smell. Diamines typically have a pungent smell. For instance, cadaverine and putrescine, depicted in Figure 1, are two molecules responsible for decaying tissue.
01:25Mutagenicity and Carcinogenicity
Mutagenicity and carcinogenicity refer to the ability of drugs to cause genetic defects and induce cancer, respectively. The International Agency for Research on Cancer (IARC) classifies agents into four groups based on their carcinogenic potential. Group 1 agents are known human carcinogens; group 2A agents are probably carcinogenic to humans; group 3 agents lack data to support their role in carcinogenesis; and group 4 includes agents for which data support that they are not likely to be...