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Updated: Dec 31, 2025

Precision Implementation of Minimal Erythema Dose MED Testing to Assess Individual Variation in Human Inflammatory Response
Published on: October 3, 2019
Photopatch Testing Among Members of the American Contact Dermatitis Society
Taehan Kim1, James S Taylor, Howard I Maibach
1From the *Department of Dermatology, Stanford University School of Medicine, CA †Department of Dermatology, Cleveland Clinic Lerner College of Medicine, OH ‡Department of Dermatology, University of California San Francisco School of Medicine.
Background:
Photopatch testing is an important diagnostic tool in evaluating patients with suspected photoallergic contact dermatitis. Although protocols for photopatch testing have been described, there are no consensus recommendations by the American Contact Dermatitis Society (ACDS).
Objectives:
The aims of this study were to examine the common practices of photopatch testing among ACDS members and to review and compare commonly used photoallergen series.
Methods:
We conducted a questionnaire-based survey among ACDS members via e-mail to inquire about their photopatch test methods. We compared the results with the European consensus methodology and reviewed photoallergen series reported by the respondents.
Results:
Of the 791 members contacted, 112 members (14%) responded to the survey. Among these, 50 respondents (45%) perform photopatch testing, approximately half of whom (48%) determine minimal erythema dose before the test using UVA with or without UVB irradiation. Respondents use a total of 13 photoallergen series, alone or in any combination, as well as customized series.
Conclusions:
These results have potential to aid clinicians in identifying photoallergen series best suited for their patients and suggest a need for consensus recommendations by the ACDS.

