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Updated: Dec 31, 2025

High-Resolution Endocardial and Epicardial Optical Mapping in a Sheep Model of Stretch-Induced Atrial Fibrillation
Published on: July 29, 2011
An atrial fibrillation rotor, mapped conventionally
Niraj Varma1, Raymond Rizzo1, Brian Wisnoskey1
1Department of Cardiac Electrophysiology, Heart and Vascular Institute, Cleveland Clinic, Cleveland, Ohio.
Atrial fibrillation (AF) may involve rotational activity and reentry mechanisms. Even if these rotors break apart, AF can persist, suggesting complex underlying causes for this heart rhythm disorder.
Area of Science:
- Cardiology
- Electrophysiology
- Medical Sciences
Background:
- Atrial fibrillation (AF) is a common arrhythmia with complex mechanisms.
- Understanding the precise drivers of AF is crucial for developing effective treatments.
- Previous research suggests various potential mechanisms, including focal triggers and reentrant circuits.
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