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Cardiac Versus Renal Response to Volume Expansion in Preclinical Systolic Dysfunction With PDEV Inhibition and BNP

Siu-Hin Wan1,2, Isabel Torres-Courchoud3, Paul M McKie1,2

  • 1Department of Cardiovascular Diseases, Mayo Clinic and Foundation, Rochester, Minnesota.

JACC. Basic to Translational Science
|January 8, 2020
PubMed

Keywords:
ACC, American College of CardiologyAHA, American Heart AssociationANP, atrial natriuretic peptideB-type natriuretic peptideBNP, B-type natriuretic peptideGFR, glomerular filtration rateHF, heart failureLAVI, left atrial volume indexLVEDV, left ventricular end-diastolic volumeLVEF, left ventricular ejection fractionLVESV, left ventricular end-systolic volumeNP, natriuretic peptidePDEV, type V phosphodiesterasePSD, preclinical systolic dysfunctionRPF, renal plasma flowSC, subcutaneousVE, acute saline volume expansioncGMP, cyclic guanosine monophosphatecardiorenalheart failurenesiritidephosphodiesterase inhibitionsystolic dysfunction

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