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Updated: Dec 31, 2025

Diagnosis of Neoplasia in Barrett’s Esophagus using Vital-dye Enhanced Fluorescence Imaging
Published on: May 11, 2014
Linked Color Imaging Highlights Flat Early Gastric Cancer
Kimitoshi Kubo1, Noriko Kimura2, Soichiro Matsuda1
1Department of Gastroenterology, National Hospital Organization Hakodate National Hospital, Hakodate, Japan.
Abstract:
While linked color imaging (LCI) may allow flat early gastric cancer to be detected early, the endoscopic and pathological features of lesions detected by LCI remain poorly described. Screening esophagogastroduodenoscopy performed on a 68-year-old woman revealed a yellowish, flat lesion shown to be reddish in its central area, located in the anterior wall of the gastric lower body on white light imaging (WLI). On LCI, the lesion was highlighted as an orangish, flat lesion shown to be purple-colored in its central area, surrounded by lavender-colored tissue. Endoscopic submucosal dissection performed led to the patient being diagnosed with tubular adenocarcinoma, well-differentiated type (tub1), pT1a (M). This case suggests that LCI may prove more useful than WLI for the detection of flat early gastric cancer lesions.
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