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Inhibition of neutrophil and monocyte functions by the monoclonal antibody TM2
A Takeuchi1, A Shimizu, H Ohto
1Second Department of Medicine, University of Teikyo, Tokyo, Japan.
Clinical Immunology and Immunopathology
|December 1, 1988
Abstract:
The ability of the monoclonal antibody termed TM2 to inhibit chemiluminescence generation by granulocytes and monocytes was examined. TM2 could inhibit the chemiluminescence generation of these cells when they were stimulated by all the stimuli presented. It seems that TM2 binds to the surface antigen of phagocytic cells which is important in the generation of free radicals.