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Bacterial enzymes for lignin depolymerisation: new biocatalysts for generation of renewable chemicals from biomass
Timothy D H Bugg1, James J Williamson1, Goran M M Rashid1
1Department of Chemistry, University of Warwick, Coventry, CV4 7AL, United Kingdom.
Abstract:
The conversion of polymeric lignin from plant biomass into renewable chemicals is an important unsolved problem in the biorefinery concept. This article summarises recent developments in the discovery of bacterial enzymes for lignin degradation, our current understanding of their molecular mechanism of action, and their use to convert lignin or lignocellulose into aromatic chemicals. The review also discusses the recent developments in screening of metagenomic libraries for new biocatalysts, and the use of protein engineering to enhance lignin degradation activity.
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