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Related Concept Videos

Glaucoma: Overview01:25

Glaucoma: Overview

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Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
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Open Angle Glaucoma: Treatment01:27

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In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
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Angle Closure Glaucoma: Treatment01:28

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Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
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Updated: Dec 31, 2025

Glaucoma-inducing Procedure in an In Vivo Rat Model and Whole-mount Retina Preparation
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Glaucoma in pregnancy: an update.

Bryan Strelow1, David Fleischman

  • 1Department of Ophthalmology, University of North Carolina, Chapel Hill, North Carolina, USA.

Current Opinion in Ophthalmology
|January 11, 2020
PubMed
Summary
This summary is machine-generated.

Managing glaucoma in pregnant patients requires balancing maternal health with fetal safety. Surgical options, including traditional and minimally invasive glaucoma surgery (MIGS), may be considered, while new medications have limited safety data for pregnancy.

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Area of Science:

  • Ophthalmology
  • Maternal-Fetal Medicine

Background:

  • Glaucoma management during pregnancy presents a significant clinical challenge due to the need to balance maternal disease control with potential risks to fetal development.
  • Limited systematic studies exist regarding the safety of glaucoma interventions in pregnant populations, necessitating a review of available data.

Purpose of the Study:

  • To review and synthesize data from observational studies and case reports on the safety of glaucoma interventions during pregnancy.
  • To provide guidance and context for clinicians managing glaucoma in pregnant patients.

Main Methods:

  • Literature review of observational studies and case reports concerning glaucoma treatment in pregnancy.
  • Analysis of surgical glaucoma procedures, including traditional (trabeculectomy, tube-shunts) and newer minimally invasive glaucoma surgery (MIGS) techniques.
  • Evaluation of available data on newer glaucoma medications (Vyzulta, Rhopressa) for pregnant patients.

Main Results:

  • Surgical interventions, such as orphan trabeculectomy or MIGS procedures like the gelatin stent, may be viable options for severe glaucoma in pregnancy.
  • Newer medications like Vyzulta and Rhopressa have limited safety data for use during pregnancy.
  • Minimizing systemic absorption is crucial when glaucoma medications are necessary.

Conclusions:

  • Glaucoma management during pregnancy necessitates a multidisciplinary approach involving obstetrics and neonatology.
  • Surgical management should be considered for pregnant patients, potentially preceding medical management to minimize fetal exposure.
  • Careful consideration of fetal health is paramount in all treatment decisions for pregnant glaucoma patients.