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Related Experiment Video

Updated: Dec 31, 2025

A New Technique for Quantitative Analysis of Hair Loss in Mice Using Grayscale Analysis

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Published on: March 9, 2015

Fibrosing alopecia in a pattern distribution.

Jacob Griggs¹, Ralph M Trüeb², Maria Fernanda Reis Gavazzoni Dias³

¹Dr Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, Florida.

Journal of the American Academy of Dermatology

|January 12, 2020

Summary

Fibrosing alopecia in a pattern distribution (FAPD) is a scarring alopecia with features of androgenetic alopecia and lichen planopilaris. Early diagnosis and combined therapies targeting inflammation and hair growth are crucial for managing FAPD.

Keywords:

FAPD androgenetic alopecia central centrifugal cicatricial alopecia cicatricial alopecia fibrosing alopecia in a pattern distribution frontal fibrosing alopecia lichen planopilaris scarring alopecia

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Published on: June 25, 2014

Area of Science:

Dermatology
Trichology
Pathology

Background:

Fibrosing alopecia in a pattern distribution (FAPD) is a recently identified condition.
It shares features with androgenetic alopecia (AGA) and lichen planopilaris.
A review of current literature on FAPD is presented.

Purpose of the Study:

To review the existing literature on FAPD.
To consolidate understanding of its epidemiology, pathogenesis, clinical presentation, diagnosis, and treatment.

Main Methods:

Comprehensive PubMed searches were conducted to identify relevant articles on FAPD.
References from identified articles were cross-referenced to find additional studies.

Main Results:

A total of 15 articles were analyzed, encompassing 188 patients (164 women, 24 men).
The average age of affected individuals was 53.8 years.

Conclusions:

FAPD affects androgen-dependent scalp areas, showing hair follicle miniaturization and features of both lichen planopilaris and AGA.
It may result from an exaggerated inflammatory response to AGA-triggered follicular damage.
Diagnosis relies on physical examination, trichoscopy, and biopsy; misdiagnosis as AGA with seborrheic dermatitis is possible. Combined anti-inflammatory and hair growth-promoting therapies are suggested.