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FG 7142: is this validated tool to study anxiety now forgotten?
1Antaxios GmbH, Zum Weiher 44, 14552, Wildenbruch, Germany. r.horowski@antaxios.de.
Journal of Neural Transmission (Vienna, Austria : 1996)
|January 14, 2020
Summary
FG 7142, a novel drug, induced severe anxiety attacks in its first human trial. This finding suggests its potential as a tool for future anxiety research.
Area of Science:
- Psychopharmacology
- Neuroscience
- Clinical Psychology
Background:
- FG 7142 is a compound investigated for its effects on the central nervous system.
- Previous preclinical studies hinted at its potential to modulate anxiety-related pathways.
Observation:
- This report details the first administration of FG 7142 to human subjects in a Phase I clinical study.
- Participants experienced significant and severe anxiety attacks following drug administration.
Findings:
- The human experience with FG 7142 confirms its potent anxiogenic properties.
- The severity of induced anxiety attacks was notable and consistent across observed subjects.
Implications:
- FG 7142 represents a potential pharmacological tool for experimentally inducing and studying anxiety in humans.
- This validated tool could advance research into the neurobiology and treatment of anxiety disorders.
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