Management of Optic Disk Pit-associated Macular Detachment with Human Amniotic Membrane Patch

Area of Science:

• Ophthalmology
• Retinal Surgery

Background:

• Optic nerve head pits can cause serous macular detachment, leading to vision impairment.
• Current treatments for this condition have limitations.

Purpose of the Study:

• To introduce and evaluate a new surgical technique for treating serous macular detachment associated with optic nerve head pits.
• To assess the efficacy of a human amniotic membrane patch in this specific condition.

Main Methods:

• A minimally invasive pars plana vitrectomy was performed on three patients.
• A human amniotic membrane patch was implanted into the optic nerve pit.
• Air was used as an endotamponade, with patients maintaining a face-down position post-surgery.

Main Results:

• Subretinal fluid resolved gradually over a 6-month follow-up period.
• Visual acuity improved significantly, reaching 20/25 by the sixth month.
• No recurrence of subretinal fluid or postoperative complications were observed.

Conclusions:

• Human amniotic membrane patching is a potentially effective surgical option for optic disc pit maculopathy.
• The technique demonstrated encouraging visual acuity recovery and a favorable safety profile.