Association between Helicobacter pylori Infection and Colorectal Adenomatous Polyps

Helicobacter pylori infection is a common chronic infection worldwide. At the same time, the incidence of colorectal adenomatous polyps is also at high levels. In order to assess the relationship between Helicobacter pylori infection and the occurrence of colorectal adenomatous polyps, we observed 166 patients who had undergone an electronic colonoscopy and ¹³C urea breath test in the outpatient clinic.

A total of 166 (87 males and 79 females, aged 53.85 ± 9.18 years) patients who had colonoscopy examination and ¹³C urea breath test were divided into a Helicobacter pylori-positive group (n = 68) and Helicobacter pylori-negative group (n = 98) by the ¹³C urea breath test. At the same time, total cholesterol, triglycerides, and fasting blood sugar were measured and the occurrence of hypertension was counted.

Patients with Helicobacter pylori infection had higher incidence of colorectal adenomatous polyps and multiple colorectal adenomatous polyps, higher levels of total cholesterol and fasting glucose, and more males (P < 0.05, P < 0.01). It was found that Helicobacter pylori infection (P < 0.05, OR 2.383) was significantly associated with the risk of colorectal adenomatous polyps by binary logistic regression analysis.

Patients with Helicobacter pylori infection had higher incidence of colorectal adenomatous polyps.