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Related Concept Videos

Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

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Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
862
Inflammatory Bowel Disease I: Ulcerative Colitis01:27

Inflammatory Bowel Disease I: Ulcerative Colitis

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Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
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Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

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Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
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Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy01:30

Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy

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Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
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Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

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Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
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Appendicitis-II: Diagnostic Studies and Management01:29

Appendicitis-II: Diagnostic Studies and Management

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Diagnosing and managing appendicitis requires a structured and comprehensive approach that spans from initial assessment to postoperative care. Here is an overview of the process:
Diagnosing Appendicitis
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The DICA endoscopic score and the CODA clinical score may predict the severity of acute diverticulitis and the risk of hospitalisation: results from an international multicentre prospective cohort study.

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Murine Distal Colostomy, A Novel Model of Diversion Colitis in C57BL/6 Mice
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Critical Issues on Diverticular Disease.

Neil Stollman1, Marcello Picchio2, Sebastiano Biondo3

  • 1Division of Gastroenterology, Alta Bates Summit Medical Center, East Bay Center for Digestive Health, 300 Frank H Ogawa Plaza, Oakland, CA, USA. neil@stollman.com.

Journal of Gastrointestinal and Liver Diseases : JGLD
|January 14, 2020
PubMed
Summary
This summary is machine-generated.

Outpatient management for uncomplicated diverticulitis is safe for selected patients. Segmental colitis associated with diverticulosis (SCAD) is a distinct condition, and diverticular inflammation does not increase long-term colorectal cancer risk.

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Area of Science:

  • Gastroenterology
  • Colorectal Surgery
  • Internal Medicine

Background:

  • Diverticular disease presents complex clinical challenges.
  • Current management strategies require critical evaluation.
  • Understanding associated conditions and risks is crucial.

Purpose of the Study:

  • To evaluate the safety and efficacy of outpatient management for uncomplicated diverticulitis.
  • To define Segmental Colitis Associated with Diverticulosis (SCAD) and its characteristics.
  • To investigate the relationship between diverticular inflammation and colorectal cancer risk.

Main Methods:

  • Review of current clinical practices and evidence for diverticulitis management.
  • Analysis of pathological findings and clinical presentation of SCAD.
  • Longitudinal assessment of colorectal cancer incidence in patients with diverticular disease.

Main Results:

  • Outpatient management is safe and cost-effective for selected uncomplicated diverticulitis patients.
  • Non-antibiotic treatment is viable for carefully selected outpatient cases.
  • SCAD is a biopsy-diagnosed entity with IBD-like pathology, primarily in the sigmoid colon.
  • Diverticular inflammation is associated with colorectal cancer within 18 months of diagnosis, likely due to misclassification; risk does not increase thereafter.

Conclusions:

  • Selected patients can safely undergo outpatient management for uncomplicated diverticulitis.
  • SCAD is a distinct pathological entity requiring specific treatment considerations.
  • Colorectal cancer screening is recommended after the initial 18 months following a diverticulitis diagnosis to rule out misclassification.