Related Experiment Video
Updated: Dec 31, 2025

Sub-nanometer Resolution Imaging with Amplitude-modulation Atomic Force Microscopy in Liquid
Published on: December 20, 2016
Image reconstruction for sub-sampled atomic force microscopy images using deep neural networks
1Division of Systems Engineering, Boston University, Boston, MA 02215, USA.
Abstract:
Undersampling is a simple but efficient way to increase the imaging rate of atomic force microscopy (AFM). One major challenge in this approach is that of accurate image reconstruction from a limited number of measurements. In this work, we present a deep neural network (DNN) approach to reconstruct μ-path sub-sampled AFM images. Our network consists of two sub-networks, namely a RED-net and a U-net, in series, and is trained end-to-end from random images masked according to μ-path sub-sampling patterns. Using both simulation and experiments, the DNN is shown to yield better image quality than three existing optimization-based methods for reconstruction: basis pursuit, a variant of total variation minimization, and inpainting.
Related Concept Videos
Atomic Force Microscopy
The AFM Probe
The probe is regarded as the heart of any AFM setup and comprises the...
Electron Microscope Tomography and Single-particle Reconstruction
Electron Tomography
Electron tomography can be performed either in TEM or STEM (scanning transmission...

