Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Aortic Regurgitation I: Introduction

Aortic Regurgitation I: Introduction

IntroductionAortic regurgitation is characterized by the backward flow of blood from the aorta into the left ventricle during diastole and arises from the improper closure of the aortic valve. This condition results in left ventricular volume overload and can stem from both acute and chronic etiologies, each contributing uniquely to the disease's progression and symptomatology.Acute and Chronic CausesAcute aortic regurgitation often results from events that suddenly impair the integrity of the...

Aortic Regurgitation II: Clinical Features and Diagnostic Tests

Aortic Regurgitation II: Clinical Features and Diagnostic Tests

Aortic valve regurgitation (AR) occurs when the aortic valve fails to close properly, allowing blood to flow backward from the aorta into the left ventricle. This backflow can result in two distinct clinical presentations: acute and chronic AR, each characterized by its own set of symptoms and physical findings.Acute Aortic RegurgitationAcute AR presents with a sudden onset of severe symptoms. Patients typically experience profound dyspnea (shortness of breath), chest pain, and signs of left...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

<i>Aerococcus urinae</i> endocarditis in a teenager with CHD: a rare paediatric presentation.

Cardiology in the young·2026

Same author

Navigating the Intersection of Complex Anatomy and Extreme Physiology in Adult Congenital Heart Disease.

JACC. Case reports·2026

Same author

Interferon-γ and interleukin-17A associations with vascular dysfunction following paediatric cardiac surgery with cardiopulmonary bypass.

Cardiology in the young·2026

Same author

Single Ventricle: Radiology Primer for Preprocedural Evaluation.

Radiographics : a review publication of the Radiological Society of North America, Inc·2026

Same author

Resolution of Fetal Arrhythmia Following Maternal Discontinuation of Doxylamine (Unisom): A Case Report and Review.

Cureus·2026

Same author

Supraclavicular Approach for Arteria Lusoria in Pediatric Patients.

Annals of thoracic surgery short reports·2025

Same journal

Pulmonary artery sling repair via left thoracotomy.

Cardiology in the young·2026

Same journal

Post-COVID paediatric dysautonomia: never the heart, always the brain-myth or maxim?

Cardiology in the young·2026

Same journal

Emotional intelligence: An added metric of neurodevelopment in a CHD cohort.

Cardiology in the young·2026

Same journal

Case-based learning in paediatric cardiology training.

Cardiology in the young·2026

Same journal

A scoping review of the evidence supporting antiarrhythmic use after paediatric cardiac surgery.

Cardiology in the young·2026

Same journal

Dexrazoxane in children receiving anthracyclines: efficacy, safety, and region-specific considerations for Latin America.

Cardiology in the young·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Dec 31, 2025

Direct Re-implantation of Left Coronary Artery into the Aorta in Adults with Anomalous Origin of Left Coronary Artery from the Pulmonary Artery ALCAPA

Direct Re-implantation of Left Coronary Artery into the Aorta in Adults with Anomalous Origin of Left Coronary Artery from the Pulmonary Artery ALCAPA

Published on: April 24, 2017

Truncus arteriosus with retrograde aortic flow: a unique case.

Matthew A Solomon¹, Bijoy Thattaliyath¹, Ravi Ashwath¹

¹Department of Pediatric Cardiology, Stead Family Children's Hospital, University of Iowa, Iowa City, IA, USA.

Cardiology in the Young

|January 15, 2020

Summary

This summary is machine-generated.

This study reports a rare case of truncus arteriosus in a neonate where the ascending aorta received blood flow in reverse. This finding challenges typical understandings of congenital heart defect blood flow dynamics.

Keywords:

Truncus arteriosus aortic hypoplasia retrograde aortic flow retrograde blood flow valve dysplasia

More Related Videos

O-Ring Aortic Banding Versus Traditional Transverse Aortic Constriction for Modeling Pressure Overload-Induced Cardiac Hypertrophy

O-Ring Aortic Banding Versus Traditional Transverse Aortic Constriction for Modeling Pressure Overload-Induced Cardiac Hypertrophy

Published on: October 6, 2022

Modified Octopus Technique for Thoracoabdominal Aortic Aneurysm

Modified Octopus Technique for Thoracoabdominal Aortic Aneurysm

Published on: August 1, 2025

Related Experiment Videos

Last Updated: Dec 31, 2025

Direct Re-implantation of Left Coronary Artery into the Aorta in Adults with Anomalous Origin of Left Coronary Artery from the Pulmonary Artery ALCAPA

Direct Re-implantation of Left Coronary Artery into the Aorta in Adults with Anomalous Origin of Left Coronary Artery from the Pulmonary Artery ALCAPA

Published on: April 24, 2017

O-Ring Aortic Banding Versus Traditional Transverse Aortic Constriction for Modeling Pressure Overload-Induced Cardiac Hypertrophy

O-Ring Aortic Banding Versus Traditional Transverse Aortic Constriction for Modeling Pressure Overload-Induced Cardiac Hypertrophy

Published on: October 6, 2022

Modified Octopus Technique for Thoracoabdominal Aortic Aneurysm

Modified Octopus Technique for Thoracoabdominal Aortic Aneurysm

Published on: August 1, 2025

Area of Science:

Pediatric Cardiology
Congenital Heart Disease
Neonatal Physiology

Background:

Truncus arteriosus is a rare cyanotic congenital heart defect.
It results from the failure of septation of the arterial outflow tract.
Typically, the ascending aorta is supplied by anterograde flow through the truncal valve.

Observation:

A unique case of neonatal truncus arteriosus was identified.
The ascending aorta in this case was supplied entirely by retrograde blood flow.
This represents a previously unreported morphological variation.

Findings:

The study details the first reported instance of truncus arteriosus with retrograde ascending aorta flow.
This challenges the conventional understanding of hemodynamics in this condition.
The specific anatomical variations leading to this retrograde flow are highlighted.

Implications:

This case expands the spectrum of known truncus arteriosus morphologies.
It may necessitate re-evaluation of diagnostic and surgical approaches for similar cases.
Further research into the embryological basis of such retrograde flow is warranted.